The genetic analysis of the Rubinstein-Taybi syndrome (RTS, OMIM 180849) may shed light on mechanisms of transcription, brain function, keloid formation, and cancer. RTS can be caused by heteroallelic mutations of CREBBP (the gene for cAMP responsive element binding (CREB) binding protein). Human CREBBP resides on chromosome 16p13.3, spans approximately 150 kb at the genomic level, and comprise...

BACKGROUND The aims of this systematic review and meta-analysis of randomized controlled trials are to evaluate the effects of active heated humidifiers (HHs) and moisture exchangers (HMEs) in preventing artificial airway occlusion and pneumonia, and on mortality in adult critically ill patients. In addition, we planned to perform a meta-regression analysis to evaluate the relationship between ...

Abstract Study question Do gut microbial composition and functionality differ between women with without endometriosis? Summary answer Gut microbiome diversity (species pathways) were not significantly different endometriosis. What is known already Endometriosis, defined as the presence of endometrial-like tissue outside uterus, one most common female reproductive disorders. Although theories p...

wetlands as a situ for the growth of native plants, as a habitat for certain species of fish and aquatic birds, and because of their potential economic, cultural and recreational services, are valuable heritage so their protection and conservation is very essential. mostly due to the absence of wetlands services’ valuation, lack of special regulations, and lack of guarantee for these properties...

Background Sjogren’s syndrome (SSj) is a systemic disease with autoimmune pathogenesis, prevalent involvement of the lacrimal and salivary exocrine glands, classified as primary or secondary on basis association other rheumatic diseases. The epidemiological data in literature are variable due to heterogeneity populations examined different classification criteria used. In recent systematic revi...

Nest architecture and demography of the non leaf-cutting fungus-growing ant species Mycocepurus goeldii and M. smithii (Attini: Formicidae) were studied in an agroforest habitat near Manaus, Brazil during the excavation of 13 nests. Both species built their nests in two different ways. The first type possessed a “tree-like” architecture, in which a vertical tunnel led downwards and lateral tunn...

Data mining is an emerging field of study in Information Systems programs. The purpose of this tutorial is to provide a hands-on approach on how to utilize SQL Server 2008 Business Intelligence platforms to teach a senior level data mining methods class in an Information Systems program. Our intention is to highlight the capabilities of the platform to faculty currently teaching a business inte...

Introduction: High resolution EPI at high field is severely affected by T2* relaxation and susceptibility artifacts. To address both effects and to keep the echo-time (TE) short, the EPI readout duration must be reduced, which can be achieved using parallel imaging [1]. For sub-millimeter fMRI in humans large acceleration factors (AF) are essential, which are feasible at high field strength [2]...