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تعداد نتایج: 196 فیلتر نتایج به سال:
Patients with diabetes are at a higher risk of having diabetic foot ulcers (DFUs) or necrotizing fasciitis (NF). The present study aims to examine the clinical characteristics and associated risk factors for lower-extremity amputation (LEA) in patients with DFU complicated by NF.We retrospectively reviewed patients treated at a major diabetic foot center in Taiwan between 2009 and 2014. Of the ...
CD6 has recently been identified and validated as risk gene for multiple sclerosis (MS), based on the association of a single nucleotide polymorphism (SNP), rs17824933, located in intron 1. CD6 is a cell surface scavenger receptor involved in T-cell activation and proliferation, as well as in thymocyte differentiation. In this study, we performed a haptag SNP screen of the CD6 gene locus using ...
Kohlmeier KA, Watanabe S, Tyler CJ, Burlet S, Leonard CS. Dual orexin actions on dorsal raphe and laterodorsal tegmentum neurons: noisy cation current activation and selective enhancement of Ca transients mediated by L-type calcium channels. J Neurophysiol 100: 2265–2281, 2008. First published July 30, 2008; doi:10.1152/jn.01388.2007. The hypocretin/orexins (Hcrt/Orxs) are hypothalamic neuropep...
Before amino acids nourish the cell they must be transported a) across the intestinal mucosa and b) across the plasma membrane of the cell where they are to be used. In addition, full consideration of their economy in the animal organism must include also their entry into the liver and their resorption from the renal tubule. All of these events appear to have much in common and probably to repr...
BACKGROUND Gangliosides may have a protective effect on the central and peripheral nervous systems. OBJECTIVES The objective of this review was to assess the effect of exogenous gangliosides in acute ischaemic stroke. SEARCH STRATEGY We searched the Cochrane Stroke Group trials register (last searched: May 2001) and contacted drug companies and main investigators of included trials. SELEC...
BACKGROUND Some have the opinion that patients cared for in Veterans Health Administration (VHA) hospitals receive care of poorer quality than those cared for in non-VHA institutions. To assess the quality of care in VHA hospitals, we compared the outcome of acute myocardial infarction among patients in VHA and non-VHA institutions while controlling for potential confounders, including coexisti...
Background and Purpose—Extracranial carotid artery (ECCA) atherosclerosis has been associated with hypertensionrelated stroke. The present study was aimed at investigating the determinants of ECCA atherosclerosis in patients with hypertension in Taiwan. Methods—The extent and severity of ECCA atherosclerosis were measured by high-resolution B-mode ultrasonography and expressed as maximal intima...
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