........................................................................................................... 223 Samenvatting ................................................................................................... 225 Curriculum Vitae ............................................................................................. 227

INTRODUCTION Characteristics of Monoclonal Antibodies, 203 Production of Monoclonal Antibodies, 207 Developing the Screening Method, 207 Generating Hybridomas, 216 Preparation for Fusions, 217 Fusions, 220 Plating Strategies, 222 Feeding Hybridomas, 224 Supernatant Collection Strategies for Screening, 224 Screening, 225 Expanding and Freezing Positive Clones, 225 Dealing with Contamination, 229...

Fine twinned microstructures with {225}γ habit planes are commonly observed in martensitic steels. The present study shows that an equibalanced combination of twin-related variants associated to the Kurdjumov-Sachs orientation relationship is equivalent to the Bowles and Mackenzie's version of the PTMC for this specific {225}γ case. The distortion associated to the Kurdjumov-Sachs orientation r...

The eggshell serves as a depository for proteins that play an important role in early embryonic development. In particular, the Drosophila eggshell is responsible for transferring asymmetries from the egg chamber to specify the regions at both ends of the embryo through the uneven activation of the Torso (Tor) receptor in its membrane. This process relies on the restricted expression of the gen...

By ERNEST BEUTLER AND DIANA HOFSTRA R ECENTLY, Holl#{225}n’ described a most interesting phenomenon : profound anemia in rats following unilateral section of the sciatic and femoral nerves. The hematologic features of this anemia were described in some detail. It was hypochromic, and the reticulocyte count was increased. There was erythroblastic hyperplasia of the marrow. Fecal urobilin excreti...

Included in the study were 57 patients with pulmonary tuberculosis hospitalized under our service in Tr#{225}nsito C#{225}ceres de Allende Hospital (C#{243}rdoba, Argentina) from 1959 to July 31, 1962. These were 39 men and 18 women with ages ranging from 13 to 54 years, most suffering from far advanced or moderately advanced pulmonary tuberculosis. These patients had been given antimicrobial t...

Targeted radiotherapies maximize cytotoxicty to cancer cells. In vivo α-generator targeted radiotherapies can deliver multiple α particles to a receptor site dramatically amplifying the radiation dose delivered to the target. The major challenge with α-generator radiotherapies is that traditional chelating moieties are unable to sequester the radioactive daughters in the bioconjugate which is c...

OBJECTIVE To summarize the diagnosis and treatment of juxta-ampullary duodenal diverticulum (JAD) in our hospital. METHODS Of 5000 consecutive endoscopic retrograde cholangiopancreatography (ERCP) performed in our department, 225 patients were diagnosed with JAD and treated. All patients were classified based on the location of Ampullae of Vater in relation to the duodenal diverticulum. Of th...

We established an interleukin 2 (IL-2)-dependent human T cell line, Kit 225, from a patient with T cell chronic lymphocytic leukemia (T-CLL) with OKT3+, -T4+, -T8- phenotype. Southern blot analysis showed that Kit 225 is not infected with human T cell leukemia/lymphoma virus (HTLV) type I or II, and is probably derived from the major clone in the fresh leukemic cells. Kit 225 cells express a la...

Chapter Outline 1. How Do New Viral Diseases Emerge? 215 1.1 Discovery of the Etiology of an Existing Disease 215 1.2 Increase in Disease Caused by an Existing Virus 216 1.3 Accumulation of Susceptible Hosts and Viral Reemergence 217 1.4 Virus New to a Specific Population 217 2. Zoonotic Infections as a Source of Emerging Viral Diseases 217 2.1 Dead-end Hosts 217 2.2 Limited Spread among Humans...