To investigate the effectiveness, safety, and tolerability of vortioxetine in patients treated at therapeutic doses (5-20mg/day) for both acute and maintenance treatment, patient-level data were pooled from 5 long-term (52-week), open-label extension studies of major depressive disorder. The mean (±standard deviation) MADRS total score improved from 17.1±10.2 at the start of maintenance therapy...

Objective: The present study examines the pattern of changes in temperament and character profiles of Obsessive Compulsive Disorder (OCD) patients following 8-20 weeks of treatment for obsessive compulsive symptoms (OC symptoms). Methodology: The study also investigated the relationship between the temperament and character pattern and the severity of OC symptoms. A sample of 52 patients who me...

Breast Cancer (BC) is the leading cause of dead in women over 25 years Mexico, there are reproductive risk factors associated with BC, these include obesity, menarche, number pregnancies, age at first childbirth, duration breastfeeding, use oral contraceptives (OC), menopause and hormonal therapy. Among factors, breastfeeding particularly interest for BC prevention. Breastfeeding Mexico has dec...

The cases of three full-term infant girls with both Hirschsprung's disease (HD) and Ondine's curse (OC) are presented, and the relevant literature is reviewed. All three patients required endotracheal intubation and assisted ventilation during the first 24 hours of life because of respiratory distress. The diagnosis of HD was subsequently established at age 13, 16, and 20 days, respectively. Th...

BACKGROUND Little is known about how hospital organizational and cultural factors associated with implementation of quality initiatives such as the Institute for Healthcare Improvement's (IHI) 100,000 Lives Campaign differ among levels of healthcare staff. DESIGN Evaluation of a mixed qualitative and quantitative methodology ("trilogic evaluation model"). SETTING Six hospitals that joined t...

Secondary organic carbon (SOC) formation and its effects on human health require better understanding in Chinese megacities characterized by a severe particulate OPEN ACCESS Atmosphere 2015, 6 362 pollution and robust economic reform. This study investigated organic carbon (OC) and elemental carbon (EC) in PM2.5 and PM0.25 collected 8–20 March 2012. Samples were collected inside and outside a c...

The aim of this prospective study was to evaluate the bone mineral density (BMD) at lumbar spine and femoral neck levels and biochemical parameters of bone turnover in 20 consecutive hyperprolactinemic males before and after an 18-month treatment with different dopamine agonists. Six patients received bromocriptine at a dose of 2.5-10 mg/day; 7 patients received quinagolide at a dose of 0.075-0...

Temporal and seasonal variations in the nocturnal activities of adult females of six locally common mosquitoes, Aedes cretinus, Ochlerotatus caspius, Oc. dorsalis, Culex pipiens, Cx. tritaeniorhynchus and Culiseta annulata were studied at Belek, Turkey, using New Jersey light traps and CO2 charged olfactory traps. In addition to assessing the relative value of these traps as sampling devices ca...