In a sustained search for novel ?-amylase inhibitors the treatment of type 2 diabetes mellitus (T2DM), we report herein synthesis series nineteen rhodanine-fused spiro[pyrrolidine-2,3?-oxindoles]. They were obtained by one-pot three component [3 + 2] cycloaddition stabilized azomethine ylides, generated in situ condensation glycine methyl ester and cyclic ketones 1H-indole-2,3-dione (isatin), w...

A recently synthesized photoactive donor named fluorinated thienyl–substituted benzodithiophene (DRTB-FT), modified with four novel end capped acceptor molecules, has been investigated through different electrical, quantum, and spectrochemical techniques for its enhanced electro-optical photovoltaic properties. DRTB-FT was connected to 2-methylenemalononitrile (D-1), 2-methylene-3-oxobutanenitr...

The central β-lactam ring of the title compound, C(23)H(21)NO(3), is almost planar (r.m.s. deviation = 0.032Å). The meth-oxy-benzene ring is almost coplanar with the β-lactam ring [dihedral angle = 1.87 (11)°], whereas the tolyl ring is almost normal to it [75.73 (12)°]. The dihedral angle between the β-lactam ring and the O-bonded phenyl ring is 51.95 (12)°. An intra-molecular C-H⋯O inter-acti...

In the title compound, C(16)H(12)BrNO(3), the butyrolactone core adopts the furan-2(5H)-one structure and forms dihedral angles of 44.80 (17) and 65.73 (18)° with the bromo-benzene and phenol rings, respectively. In the crystal, N-H⋯O and O-H⋯O hydrogen bonds link the mol-ecules, generating R(4) (3)(26) loops The edge-fused rings extend to form a chain running along the b-axis direction and C-H...

In the title compound, C(15)H(12)BrNO(2)S, the dihedral angle between the two aromatic rings is 87.81 (8)°. The five-membered thia-zolidine ring has an envelope conformation, with the S atom displaced by 0.4545 (7) Å from the mean plane of the other four ring atoms. The crystal structure exhibits O-H⋯O, C-H⋯O, C-H⋯Br and C-H⋯ π inter-actions.