results apoptosis induced by pa in ins-1 cells was significantly resolved after liraglutide treatment. simultaneously, autophagy was enhanced with the treatment of pa and liraglutide. conclusions: liraglutide appears to protect ins-1 cells from apoptosis ffa-induced by promoting autophagy. conclusions these findings provide a novel role for glp-1 analogue in preventing or treating with t2d. obj...

background: low serum 25-hydroxy vitamin d (25(oh)d) has been shown to correlate with an increased risk of type 2 diabetes mellitus (t2dm). the objective of this study was to investigate the association between serum 25(oh)d and glycemic and inflammatory markers in non-obese patients with t2dm. methods: eighty-four non-obese patients with t2dm were recruited in this cross-sectional study. demog...

background impaired fasting glucose (ifg), and impaired glucose tolerance (igt) are two prediabetes conditions which have some correlation with macrovascular disorders. the risk of microvascular complications in these groups is not clear. objectives the prevalence of albuminuria in subjects with ifg and igt was evaluated in the present study. patients and methods in this study three groups of s...

objective: to evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. materials and methods: in this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. the two groups were matched for their age and bmi. after complete observation and examination, ...

objective: to evaluate the relation between major depressions and glucose control index in type 2 diabetes mellitus. materials and methods: one- hundred thirty four patients with type 2 diabetes were enrolled in this study. hamilton rating scale for depression (ham-d) and hba1c were measured in patients. linear mixed-model analysis was applied to determine the relation between hba1c levels and ...

objective: we aimed to evaluate association between thyroid dysfunction, and lipid profile and glycated hemoglobin in type 2 diabetic patients. materials and methods: this cross-sectional study was carried out in type 2 diabetic patients who referred to yazd diabetes research center. a total of 1200 type 2 diabetic patients who had thyroid dysfunction according to clinical examinations and labo...

objective: type 2 diabetes is associated with elevated oxidative stress and decline in antioxidant defense. vitamin e supplementation reduces oxidative stress level in diabetic pa-tients. purpose of this study was to evaluate the effect of vitamin e supplementation on glycemic control and lipid profile in type 2 diabetic patients. material and methods: in this study 31 type 2 diabetic patients ...

type 2 diabetes mellitus is a chronic illness causing considerable morbidity and mortality. enormous advances have been made in medical care but more people are still having tendency to use herbal or alternative remedies. this study is a randomized, controlled trial on type 2 diabetic patients. the subject consisted of 60 patients divided randomly into three groups and supple-mented daily with ...

objective: diabetes mellitus is one of the most common metabolic disorders which have several oral complications such as hypofunction of salivary glands. the aim of present study was to compare the unstimulated whole saliva (uws) flow rate in diabetic type ii patients and healthy peoples who admitted in yazd diabetic center. materials and methods: in this analytic-observational study, 78 patien...

abstract objective: this study was carried out for investigating the religion orientation relationship with coping with diabetes in type 2 diabetic patients in yazd, iran. the present study is a kind of scientific-comparative description. the research subjects comprised of all type 2 diabetic patients admitted to the hospitals in yazd. materials and methods: the study sample was consisted of 16...