G-protein-coupled receptors (GPCRs) are involved in animal steroid hormone signaling, but their mechanism is unclear. In this research, we report that a GPCR called ErGPCR-2 controls steroid hormone 20-hydroxyecdysone (20E) signaling in the cell membrane of the lepidopteran insect Helicoverpa armigera. ErGPCR-2 was highly expressed during molting and metamorphosis. 20E, via ErGPCR-2, regulated ...

The Chinese citrus fruit fly, Bactrocera minax, is an economically important pest of citrus. It exhibits pupal diapause from November to May to combat harsh environmental conditions. Such a long pupal diapause is a barrier for laboratory rearing and development of control strategies against this pest. In the present study, 20-hydroxyecdysone (20E) was used to break pupal diapause of B. minax by...

Little is known about how the putative juvenile hormone (JH) receptor, the bHLH-PAS transcription factor MET, is involved in 20-hydroxyecdysone (20E; the molting hormone) action. Here we report that two MET proteins found in the silkworm, Bombyx mori, participate in 20E signal transduction. Met is 20E responsive and its expression peaks during molting and pupation, when the 20E titer is high. A...

de nombreux ouvrages ont été  consacrés à molière, mais ce qui est le but de ce présent article est de souligner une originalité particulière. il sera démontré que molière dénonce un tragique profond, lié à la vie des hommes et qui reste sans remède. et ceci ne se limite pas à ceux qui vivaient au xviie siècle, il nous concerne aussi. le drame évoqué par molière fait partie des obsessions de no...

Oxidative stress plays an important role in the pathological processes of ischemic brain damage. Many antioxidants have been shown to protect against cerebral ischemia injury by inhibiting oxidative stress both in vitro and in vivo. 20-Hydroxyecdysone (20E), an ecdysteroid hormone, exhibits antioxidative effects. For the work described in this paper, we used an in vitro oxidative damage model a...

Cet article confirme d’un côté que les discussions plus intéressantes du point de vue d’une pragmatique médiévale relèvent domaine théologique ; autre côté, il atténue le jugement négatif sur l’apport des œuvres logiques à l’histoire la médiévale, au moins pour xiie siècle. Il examine d’abord théories Pierre Abélard, dans rapprochement idées qui venaient Boèce et Priscien, ainsi celles ses élèv...

comment étudier les textes romanesques français si nombreux depuis la formation définitive de la langue française au xviie siècle? c'est la question à laquelle les critiques ont essayé de répondre. pourtant, de la critique traditionnelle à celle moderne, le chercheur est confronté à une diversité vertigineuse qui ne cesse de croître. suite à la nouvelle critique rassemblant les jeunes critiques...

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Mushroom bodies (MBs) are symmetrically paired neuropils in the insect brain that are of critical importance for associative olfactory learning and memory. In Drosophila melanogaster, the MB intrinsic neurons (Kenyon cells) undergo extensive reorganization at the onset of metamorphosis. A phase of rapid axonal degeneration without cell death is followed by axonal regeneration. This re-elaborati...

20-hydroxyecdysone (20E) and juvenile hormone (JH) signaling pathways interact to mediate insect development, but the mechanism of this interaction is poorly understood. Here, a calponin homologue domain (Chd) containing protein (HaCal) is reported to play a key role in the cross talk between 20E and JH signaling by varying its phosphorylation. Chd is known as an actin binding domain present in...