CVD 103-HgR is a live oral cholera vaccine strain constructed by deleting 94% of the gene for the enzymatically active A subunit of cholera toxin from classical Inaba Vibrio cholerae O1 569B; the strain also contains a mercury resistance gene as an identifying marker. This vaccine was well tolerated and immunogenic in double-blind, controlled studies and was protective in open-label studies of ...

the aim of this investigation is to compare the effect of applying two transcutaneous electrical nerve stimulation (tens) current with different frequencies (2 hz & 100 hz) on hoffmann reflex recorded from gastrosoleus muscle of healthy people. forty female subjects between 20 to 30 years of age were participated in this quasi-experimental design. twenty of them were exposed to the 100 hz curre...

An epidemic of cholera infections was documented in Haiti for the first time in more than 100 years during October 2010. Cases have continued to occur, raising the question of whether the microorganism has established environmental reservoirs in Haiti. We monitored 14 environmental sites near the towns of Gressier and Leogane during April 2012-March 2013. Toxigenic Vibrio cholerae O1 El Tor bio...

The presence of Vibrio cholerae non-O1 in water supplies for human consumption in the city of Campeche and rural locality of Bécal was investigated. V. cholerae non-O1 was detected in 5.9% of the samples obtained in deep pools of Campeche. Studies conducted in Bécal and neighbourhood of Morelos in Campeche indicated that collected samples harbored V. cholerae non-O1 in 31.5% and 8.7% respective...

OBJECTIVE We identified a poor clinical response to treatment of cholera with a single 1 g dose of ciprofloxacin, a standard treatment for cholera. METHODS To determine reasons for the poor response and better therapeutic approaches we examined the minimal inhibitor concentration (MIC, n = 275) and disc-diffusion zone sizes (n = 205) for ciprofloxacin and nalidixic acid of V. cholerae O1 stra...

Background: Recent research has explored a possible relationship between patients’ individual alpha frequency (IAF) and their response to Transcranial Magnetic Stimulation (TMS) treatment. The purpose of this study was investigate correlation IAF change in the quality life (QoL) patients with major depressive disorder (MDD). Methods: Retrospective chart review performed on 55 depression from an...

Photoacoustic microscopy (PAM) offers label-free, optical absorption contrast. A high-speed, high-resolution PAM system in an inverted microscope configuration with a laser pulse repetition rate of 100,000 Hz and a stationary ultrasonic transducer was built. Four-dimensional in vivo imaging of microcirculation in mouse skin was achieved at 18 three-dimensional volumes per second with repeated t...

Background: Orthostatic tremor (OT) is a high-frequency tremor (13–18 Hz) present in the legs when standing. Underlying disease is found in one-third of OT patients. Case Report: We describe an 86-year-old man with progressive shaking of the legs while standing, which disappears immediately after sitting down or while walking. Polymyography confirmed a tremor of the legs (10–11 Hz) while standi...