نتایج جستجو برای: 177lu
تعداد نتایج: 759 فیلتر نتایج به سال:
PSMA-TRT is approved for mCRPC based upon demonstrated overall survival (OS) advantage. However, even after pre-selection by PSMA imaging, not all patients respond (54% without PSA50 response in the VISION study). In addition to dose (which likely related both target expression and amount of radioactivity administered), prognostic genomic factors that may relate radiosensitivity exist. Collecti...
Neuroendocrine tumor (NET) occurring in association with other endocrine syndromes forms a distinct entity. The aim was to assess the therapy response profile of the routine peptide receptor radionuclide therapy (PRRT) in this relatively uncommon but clinically challenging subgroup of patients. A retrospective analysis was undertaken from the case records from those who were treated with 177Lu-...
BACKGROUND The aim of the study is to assess accuracy of activity quantification of 177Lu studies performed according to recommendations provided by the committee on Medical Internal Radiation Dose (MIRD) pamphlets 23 and 26. The performances of two scatter correction and three segmentation methods were compared. Additionally, the accuracy of tomographic and planar methods for determination of ...
Radioligand therapy with 177Lu-PSMA-617 is an innovative and effective therapy for castrate-resistant metastatic prostate cancer patients. For patients with symptomatic bone metastases without visceral metastases, the guidelines recommend radionuclide therapy with 223Ra-dichloride as a single therapeutic agent or in combination with hormone therapy. The aim of this study was to evaluate the saf...
Abstract Purpose In this work, we address image segmentation in the scope of dosimetry using deep learning and make three main contributions: (a) to extend optimize architecture an existing convolutional neural network (CNN) order obtain a fast, robust accurate computed tomography (CT)-based organ method for kidneys livers; (b) train CNN with inhomogeneous set CT scans validate daily dosimetry;...
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