Based on pharmacokinetic findings of fluorine-18labeled L-fluoroboronophenylalanine by positron emission tomography (PET), methods for estimating tumor iOB concentration were devised. In clinical practice of boron neutron capture therapy (BNCT) for high-grade gliomas, a large amount of L-boronophenylalanine (L iOB BPA)-fructose solution is used. Under these conditions, a slow i.v. infusion of L...

Profilin-1 (PFN-1) is an actin-binding protein that regulates actin polymerization, cell proliferation, apoptosis, angiogenesis, and carcinogenesis. Its dysregulation has been reported in diverse pathologic diseases; however, the role of PFN-1 psoriasis not yet elucidated. In this study, we demonstrate expression increased both skin serum patients with psoriasis. was markedly expressed epidermi...

HMN-176 ((E)-4-[[2-N-[4-methoxybenzenesulfonyl]amino]stilbazole]1-oxide) is an active metabolite of HMN-214 ((E)-4-[2-[2-(N-acetyl-N-[4-methoxybenzenesulfonyl]amino)stilbazole]]1-oxide), which has a potent antitumor activity in mouse xenograft models. In this study, we show that HMN-176 circumvents multidrug resistance in a K2 human ovarian cancer subline selected for Adriamycin resistance (K2/...

HMN-176 ((E)-4-{[2-N-[4-methoxybenzenesulfonyl]amino]stilbazole}1oxide) is an active metabolite of HMN-214 ((E)-4-{2-[2-(N-acetyl-N-[4methoxybenzenesulfonyl]amino)stilbazole]}1-oxide), which has a potent antitumor activity in mouse xenograft models. In this study, we show that HMN-176 circumvents multidrug resistance in a K2 human ovarian cancer subline selected for Adriamycin resistance (K2/AR...

Flexible perovskite solar cells (f-PSCs) are light-weight, conformal and thus ideal for seamless integration of photovoltaics onto wearable portable electronics. Nevertheless, the spread f-PSCs is limited by both lower efficiency compared to rigid counterparts employment costly materials. Among them, hole-transporting materials (HTM) represent most expensive component also a weak spot long-term...

AMA Knosala E, Wąsik G. Toxic epidermal necrolysis in a patient with lupus erythematosus. Dermatology Review/Przegląd Dermatologiczny. 2023;110(2):176-179. doi:10.5114/dr.2023.127830. APA Knosala, E., & Wąsik, (2023). Dermatologiczny, 110(2), 176-179. https://doi.org/10.5114/dr.2023.127830 Chicago Emilia, and Grażyna Wąsik. 2023. "Toxic erythematosus". Dermatologiczny 110 (2): Harvard pp.176-17...