The oxidative degradation of the oral contraceptive 17α-ethinylestradiol (EE(2)) in water by a new advanced catalytic oxidation process was investigated. The oxidant employed was hydrogen peroxide in aqueous solution and the catalyst was the iron tetra-amido macrocyclic ligand (Fe(III)-TAML) complex that has been designated Na[Fe(H(2)O)(B*)] (Fe(III)-B*). EE(2) (10 μM) was oxidised rapidly by t...

BACKGROUND Given the emerging roles of miRNAs as potential posttranscriptional/posttranslational regulators of the steroidogenic process in adrenocortical and gonadal cells, we sought to determine miRNA profiles in rat adrenals from animals treated with vehicle, ACTH, 17α-E2 or dexamethasone. Key observations were also confirmed using hormone (Bt2cAMP)-treated mouse Leydig tumor cells, MLTC-1, ...

17α-Ethynylestradiol (EE2) has gotten growing concerns due to its widely detected in the environment and high estrogenic potency. However, the knowledge on the photochemical behaviors of EE2 in natural waters is still limited. Herein, the photodegradation and estrogenic potency variation of EE2 induced nitrate were studied using a sunlight simulator consisted by a 300 W medium pressure mercury ...

We compared methods of determination of 17α-ethinyloestradiol (EE2) in surface water in Kielce, Poland. EE2 plays a role as a contraception agent and it is commonly used as an active agent in contraception pills. During studies three methods of EE2 determination were checked: TLC, HPLC, and ELISA assay. Samples of contaminated water were taken from eight points on four rivers crossing Kielce ci...

Structural modifications of natural products with complex structures like steroids require great synthetic effort. A review of literature is presented on the chemistry of the steroidal hormone 17α-methyltestosterone that is approved by Food and Drug Administration (FDA) in the United States as an androgen for estrogen-androgen hormone replacement therapy treatment. The analog also offers specia...

17 α Methyl testosterone is a synthetic steroid hormone having androgenic properties. It used in aquaculture, medical treatments, sports as doping drugs, improving food efficacy but its residue meat and their products can cause risk to the human, animals environment. In this article, we have focused on developing homologous ELISA using 17α testosterone-3-Carboxymethyloxime-Bovine serum albumin ...