OBJECTIVE To evaluate the safety of the antimicrobial peptide, lactocin 160. METHODS Lactocin 160, a product of vaginal probiotic Lactobacillus rhamnosus 160 was evaluated for toxicity and irritation. An in vitro human organotypic vaginal-ectocervical tissue model (EpiVaginal) was employed for the safety testing by determining the exposure time to reduce tissue viability to 50% (ET-50). Hemol...

« Dans quelle mesure la situation de carrefour prévention spécialisée pourrait-elle constituer une forme réponse au phénomène dit d’“incasabilitéˮ des jeunes en difficultés multiples ? ». Par cet article, nous proposerons considérer les situations d’« incasabilité » comme «...

Introduction: 160 Gbit=s optical time domain multiplexing (OTDM) technology is only interesting if full add-drop functionality can be realised on the existing fibre infrastructure [1]. A 160 Gbit=s OTDM add-drop node based on the gain transparent ultrafast nonlinear interferometer (GT-UNI) has been demonstrated under laboratory conditions [2]. In this Letter we present a 160 Gbit=s OTDM network...

Fibrin, but not fibrinogen, accelerates the activation of plasminogen catalyzed by tissue-type plaminogen activator. Previous work showed that essential information for this accelerating capacity of fibrin resides in the sequence corresponding to residues 148-160 of the A alpha chain of fibrinogen [A alpha-(148-160)]. Our working hypothesis, based on those findings, is that A alpha-(148-160) is...

Golgin-160 is a coiled-coil protein on the cytoplasmic face of the Golgi complex that is cleaved by caspases during apoptosis. We assessed the sensitivity of cell lines stably expressing wild-type or caspase-resistant golgin-160 to several proapoptotic stimuli. Cells expressing a caspase-resistant mutant of golgin-160 were strikingly resistant to apoptosis induced by ligation of death receptors...

L’article s’appuie sur un ensemble de recherches réalisées pour mettre en perspective l’exigence d’innovation qui spécifie l’ambition inclusive, au regard l’autrement capable qu’elle implique les acteurs l’école. Cette exigence ancre l’accessibilisation des environnements scolaires dans un autrement capable&#160...

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Hospitalization due to acute coronary syndromes (ACS) usually is the occasion that leads diagnosis type 2 diabetes mellitus (T2DM). Current literature suggests severity ACS could be associated with presence and DM. Purpose To study reliability HbA1c in T2DM phase ACS, as well possible correlation between ACS. Methods ...

Golgin-160, a ubiquitous protein in vertebrates, localizes to the cytoplasmic face of the Golgi complex. Golgin-160 has a large coiled-coil C-terminal domain and a non-coiled-coil N-terminal (“head”) domain. The head domain contains important motifs, including a nuclear localization signal, a Golgi targeting domain, and three aspartates that are recognized by caspases during apoptosis. Some of ...

The development of a long-acting delivery system for D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2 (RC-160), an octapeptide analog of somatostatin, required the establishment of a method for determining the concentration of this analog in serum during treatment. A sensitive and specific radioimmunoassay (RIA) for RC-160 was developed and used for following the rate of liberation of this peptide from ...

L’histoire récente de l’urbanisme peut être décrite comme une séquence trois périodes, dont la superposition est peut-être génératrice du climat d’incertitude dans lequel se déploient les modes production ville contemporaine. La première celle « l’urbanisme programmatique », seconde d’un «&#...