The asymmetric unit of the title compound, [PdCl2(C10H8N2)]·0.5C4H8O2, consists of one Pd(II) complex mol-ecule and a half-mol-ecule of 1,4-dioxane, the complete mol-ecule being generated by inversion symmetry. The Pd(II) atom has an almost square-planar coordination formed by the 2,2'-bi-pyridine ligand and two chloride ligands. Two intra-molecular C-H⋯Cl hydrogen bonds occur. In the crystal, ...

An Exposure System for Combined Administration of an Organic Solvent to Rodents by Inhalation and Water-Drinking and its Operational Performance: Hirokazu KANO, et al. Japan Bioassay Research Center, Japan Industrial Safety and Health Association—In order to obtain bioassay data for carcinogenicity and chronic toxicity of an organic solvent being absorbed into the body through multiple media by...

THE TITLE COMPOUND [SYSTEMATIC NAME: N-methyl-3-(1-naphth-yloxy)-3-(2-thien-yl)propan-1-aminium chloride], C(18)H(20)NOS(+)·Cl(-), was crystallized from 1,4-dioxane. Twofold rotational disorder exhibited by the thio-phene ring in a 0.580 (5):0.420 (5) ratio represents two different conformations of the mol-ecule that exist in the same crystal form. The crystal structure contains strong N-H⋯Cl h...

für Naturforschung in cooperation with the Max Planck Society for the Advancement of Science under a Creative Commons Attribution 4.0 International License. Dieses Werk wurde im Jahr 2013 vom Verlag Zeitschrift für Naturforschung in Zusammenarbeit mit der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. digitalisiert und unter folgender Lizenz veröffentlicht: Creative Commons Namen...

In the crystal structure of the title compound, C(17)H(16)N(2)O(3)·0.5C(4)H(8)O(2), pairs of N-H⋯N hydrogen bonds link mol-ecules into dimers with R(2) (2)(12) motifs, which are connected by N-H⋯O hydrogen bonds, forming a supra-molecular array in the ab plane. The 1,4-dioxane ring, which lies about an inversion center, adopts a chair conformation.

In this work, we describe an accelerated solid-phase synthetic protocol for ordinary or difficult peptides involving air-bath heating and amide protection. For the Hmsb-based backbone amide protection, an optimized acyl shift condition using 1,4-dioxane was discovered. The efficiency and robustness of the protocol was validated in the course of preparation of classical difficult peptides and ub...

Dioxane-based antiviral agents targeted to the hydrophobic binding pocket of Sindbis virus capsid protein were designed by computer graphics molecular modeling and synthesized. Virus production using SIN-IRES-Luc and capsid assembly were monitored to evaluate antiviral activity. A compound with a three-carbon linker chain connecting two dioxane moieties inhibited virus production by 50% at a co...

The solute-solvent interactions of L-Cysteine and L-Methionine have been studied pH metrically in various concentrations (0.060.0% v/v) 1, 4-Dioxane-water mixture maintaining an ionic strength of 0.16 mol L-1 at ambient conditions. The protonation constants have been calculated with the computer program MINIQUAD75 and the best fit chemical models are selected based on statistical parameters. Li...

Acoustic properties like partial molal volume (φ) apparent molal Compressibility(φk(s)), adiabatic compressibility(βs), intermolecular freee path length (Lf), specific acoustic impendence (Z) and relative association(RA) have been evaluated by studying ultrasonic velocities and densities of dicarboxylic acid ltaconic acid. Malonic acid, Maleic acid and Succinic acid in different percentage of d...

In the title complex, [CdCl(2)(C(4)H(8)O(2))](n), two different Cd(II) ions are present, one in a general position and one with site symmetry 2. The Cd(II) ions are coordinated by two O atoms from two 1,4-dioxane ligands and four chloride anions in a slightly distorted octa-hedral geometry and is connected to neighboring Cd(II) ions by two bridging chloride anions, generating infinite linear ch...