Astrocytes express ionotropic glutamate receptors (GluRs), and recent evidence suggests that these receptors contribute to direct signaling between neurons and glial cells in vivo. Here, we have used functional and molecular analyses to investigate receptor properties in astrocytes of human hippocampus resected from patients with pharmacoresistant temporal lobe epilepsy (TLE). Histopathological...

BACKGROUND Alien hand syndrome (AHS) is a disorder of involuntary, yet purposeful, hand movements that may be accompanied by agnosia, aphasia, weakness, or sensory loss. We herein review the most reported cases, current understanding of the pathophysiology, and treatments. METHODS We performed a PubMed search in July of 2014 using the phrases "alien hand syndrome," "alien hand syndrome pathop...

The Almahata Sitta (AhS) meteorite is a unique polymict ureilite. Recently, carbonaceous chondritic lithologies were identified in AhS. Organic matter (OM) ubiquitously found primitive chondrites. molecular and isotopic characteristics of this OM reflect its origin parent body processes, are particularly sensitive to heating. C1 AhS 671 91A investigated, focusing mainly on the OM. We that these...

BACKGROUND Anticonvulsant hypersensitivity syndrome (AHS) is a serious but poorly understood and little known disease. It has been variously described in the literature since 1934. Fatalities are rare but have been reported. METHODS A MEDLINE search was undertaken from 1991 to present, using the keywords "anticonvulsant," "phenytoin," and "hypersensitivity." English language articles and thei...

Increased numbers of corpora amylacea have been observed in the resected mesial temporal lobe of many patients with complex partial seizures (CPS) and Ammon's horn sclerosis (AHS). Several heat shock proteins (HSPs) are induced by seizures and have been suggested as an etiologic factor in the formation corpora amylacea. We quantified corpora amylacea and HSP27-immunoreactive astrocytes in tempo...

The idea of vehicle-highway communications sufficient to assume driving functions for the driver is not new. Researchers have articulated both its value and feasibility for several decades; and military and vehicle manufacturer test facility developments have proven the concept’s viability. As mounting congestion conflicts with environmental constraints, the Automated Highway System (AHS) promi...