Title: Interaction between obesity and the Hypoxia Inducible Factor 3 Alpha Subunit rs3826795 polymorphism in relation with plasma alanine aminotransferase Authors: Shuo Wang ([email protected]) Jieyun Song ([email protected]) Yide Yang ([email protected]) Yining Zhang ([email protected]) Nitesh Chawla ([email protected]) Jun Ma ([email protected]) Haijun Wang ([email protected]...

Ruiyan Du, Jinkuan Wang, Yanli Bo, Liang Cui 1 School of Information Science and Engineering, Northeastern University, Shenyang, China, [email protected] *2 Engineering Optimization & Smart Antenna Institute, Northeastern University at Qinhuangdao, Qinhuangdao, China, [email protected] 3 Environmental Management College of China, Qinhuangdao, China, [email protected] 4 Hebei Vocational and Tec...

Yixin Niu ([email protected]) Weiwei Zhang ([email protected]) Zhen Yang ([email protected]) Xiaoyong Li ([email protected]) Jie Wen ([email protected]) Suijun Wang ([email protected]) Hongmei Zhang ([email protected]) Xuanchun Wang ([email protected]) Houguang Zhou ([email protected]) Wenjun Fang ([email protected]) Li Qin ([email protected]) Qing Su (suqingxinhua@1...

Liyun Miao ([email protected]) Yongsheng Wang ([email protected]) Suhua Zhu ([email protected]) Minke Shi ([email protected]) Yan Li ([email protected]) Jingjing Ding ([email protected]) Jun Yang ([email protected]) Qing Ye ([email protected]) Hourong Cai ([email protected]) Deping Zhang ([email protected]) Hongbing liu ([email protected]) Yong Song (yong_song6310@y...

OBJECTIVE MiRNAs play crucial roles in progression of cancer. However, the underlying mechanisms of miRNAs in non small cell lung cancer are still poorly understood. The aim of this study was to investigate the expression level of microRNA-126 (miR-126) and microRNA-133b (miR-133b) and also their association with clinicopathological features in patients with non small cell lung cancer (NSCLC). ...

The present study aimed to explore microRNA-126 (miR-126) as a novel therapeutic target for primary hypertension. The lentiviral vector containing human immunodeficiency virus 1 (HIV‑1), the miR‑126 gene knockdown viral vector (lenti-miR-126-KD), and control lentiviral vector (lenti‑scramble‑miR) were constructed. Spontaneously hypertensive rats were randomly divided into 4 groups, which receiv...

BACKGROUND MicroRNAs (miRNAs) are important post-transcriptional regulators. Altered expression of miRNAs has recently demonstrated association with human ulcerative colitis (UC). In this study, we attempted to elucidate the roles of miR-126 in the pathogenesis of UC. METHODS Expression of miR-126, miR-21, miR-375 and the potential targets NF-κB inhibitor alpha (IκBα, IKBA or NFKBIA), Polo-li...

OBJECTIVE The purpose of this study was to examine sensory function and albumin excretion according to categories of glucose tolerance in individuals undergoing screening for diabetes. RESEARCH DESIGN AND METHODS Sensory function and albumin excretion measurements were obtained in 636 individuals at the time of screening for diabetes according to American Diabetes Association glucose toleranc...

Disruption of the homeostasis of oxygenated regulatory lipid mediators (oxylipins), potential markers of exposure to aryl hydrocarbon receptor (AhR) agonists, such as 3,3',4,4',5-pentachlorobiphenyl (PCB 126), is associated with a range of diseases, including nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Here we test the hypothesis that PCB 126 exposure alters the levels of...

We investigated the biological significance of microRNA-126 (miR-126) expression in patients with atrial fibrillation (AF) and/or heart failure (HF) to examine the possible mechanism of miR-126-dependent AF and development of HF. A total of 103 patients were divided into three groups: AF group (18 men and 17 women, mean age: 65.62±12.72 years), HF group (17 men and 15 women, mean age: 63.95±19....