Patient Age, y/sex Occupation Hospital Days with fever after possible tick bite Symptom onset Fever Rash Additional symptom/sign Underlying disorder Laboratory findings (reference values)† Treatment 1 87/F Farmer A 5 d after working on farm 2010 May 39.7C Yes Malaise Hypertension, hyperlipidemia WBC, 8.7 × 10 cells/L (3.5–9.2 × 10 cells/L); Plt, 196 × 10 cells/L (155–365 × 10 cells/L); AST, 145...

The blood-brain barrier (BBB) transport and metabolism of a novel arginine-vasopressin fragment 4-9 [AVP(4-9), isoelectric point; (pI) = 9.2] analog, that is, cationic AVP(4-9) (C-AVP(4-9), PI = 9.8), were examined in vivo and in vitro. At 45 min after an i.v. administration to mice, the cerebrum-to-plasma concentration ratios of (35)S-labeled AVP(4-9) and (125)I-labeled C-AVP(4-9) were 0.103 a...

Epithelial cells line the lumens of organs including the gastrointestinal tract, kidney tubules and respiratory airways, where they regulate the transport of electrolytes and the movement of macromolecules. The current study aimed to investigate the transport of IGF-I across epithelial cell barriers. Epithelial cell lines derived from gut (IEC-6), kidney (MDBK) and lung (Mv1Lu) were shown to po...

Differential diagnosis between tuberculous peritonitis and peritonitis carcinomatosis is extremely difficult in patients with ascites, peritoneal implants and elevated CA 125 level. A 16-year-old girl presented with abdominal distention, intermittent fever and weight loss. Physical examination and radiologic studies revealed massive ascites, generalized peritoneal thickening and slightly enlarg...

Abstracts for oral presentationss for oral presentations I. Kiss A, Juhász L, Huliák I, Végh Á. Az exogén peroxinitrit hatása az okklúziós és reperfúziós arrhythmiákra altatott kutyákban (2006). Magyar Élettani Társaság LXX. Vándorgyűlése, Szeged. Abstract book:125: E67. II. Juhász L, Kiss A. Az exogén peroxinitrit hatása az okklúziós és reperfúziós arrhythmiákra altatott kutyában (2007). SZTE ...

Microbial cell factories express diverse heterologous pathways for the production of a wide range valuable natural products. However, recovery and purification such compounds is major bottleneck in commercialization. In this study, novel situ solid phase adsorption strategy was investigated enhanced taxadiene, precursor to blockbuster anticancer drug, paclitaxel, from engineered Saccharomyces c...

conclusions these results show that zen and α-zol enhance the rate of cell division in er positive cells and therefore, exposure to this mycotoxin may increase the risk of breast cancer. results the results obtained from the present study demonstrated that both zen and α-zol enhance the cell viability of mcf-7 especially at low doses (1 - 500 ng/ml) and at a high dose of 125µg/ml after 24 and 4...

Interaction of microgram quantities of highly purified rabbit anti-TNP antibodies with TNP-substituted HeLa, HEp-2, and L cells caused an intense stimulation of radioactive nucleoside ([(125)I]UdR and [(3)H]TdR) uptake which was maximal 24-72 h after exposure of cells to antibody. The stimulation of nucleoside uptake and presumaly DNA synthesis was shown to be immuno logically mediated because ...

background: sustainable and commercial production of secondary metabolites is a critical issue when dealing with its clinical application. efforts are still being made to look for biotic or abiotic elicitors with more efficient and universal effects on the improvement of secondary metabolites. objective: in order to evaluate the suitability of different biotic elicitors on p. harmala l. cell su...