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Dear Editor, t is a great pleasure to receive two valuable comments about our article regarding sudden cardiac death (SCD) in young athletes from two well known experts working in the field of preparticipation evaluation and prevention of sports injuries. We, as authors, generally agree with both authors' comments. However, some considerations should be re-emphasized here. Dr. Patel has mention...
Experiments were designed to separate effects of myocardial oxygen tension and oxygen consumption on coronary autoregulation. The approach was to measure coronary hemodynamic and metabolic responses to decreases in perfusion pressure during interventions that altered the balance between myocardial oxygen supply and demand. Studies were conducted in anesthetized heart-blocked dogs with the left ...
BACKGROUND The aim of this study was to present and compare the results of proposed methods for optimal red cell mass and plasma volume (RCM&PV) estimation, and their influence on the interpretation of obtained results. MATERIAL AND METHODS In 120/280 patients with polycythaemia rubra vera, subjected to RCM&PV determination with autologous erythrocytes in vitro labelled with 51Cr-sodium chrom...
Background GSK3532795 is a second-generation human immunodeficiency virus type 1 (HIV-1) maturation inhibitor that targets HIV-1 Gag, inhibiting the final protease cleavage between capsid protein p24 and spacer protein-1, producing immature, noninfectious virions. Methods This was a phase 2a, randomized, dose-ranging multipart trial. In part A, subtype B-infected subjects received 5-120 mg GS...
This phase I study aimed at determining the maximum tolerated dose (MTD) and characterizing the safety, tolerability, pharmacokinetics (PKs), and efficacy of pasireotide in patients with advanced neuroendocrine tumors (NETs). Patients were enrolled in two phases: dose-escalation phase (to determine the MTD) at a starting dose of 80 mg pasireotide long-acting release (LAR) i.m. followed by a dos...
-40.0 -20.0 0.0 20.0 40.0 60.0 80.0 100.0 120.0 140.0 160.0 180.0 Food Price Index in USD -annualIndex Trend Cycle -40 -20 0 20 40 60 80 100 120 Food Price Index in SDR -annualIndex Trend Cycle By Eugenio Díaz-Bonilla, Inter-American Development Bank Juan Francisco Ron, Inter-American Development Bank Issue Paper No. 28 ICTSD Programme on Agricultural Trade and Sustainable Development November ...
he response of Isa Brown laying hens during 77–85 weeks age to peeled unfermented cassava root meal (CRM) as total substitute for maize in diet was examined. Eighty (80) were assigned four dietary treatment groups (T1,T2,T3 and T4) a completely randomized design. The control (CD) contained 40% while the proportion CD replaced with 100, 110 120% CRM amounting 40, 44 48% T2, T3, T4 respectively. ...
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