نتایج جستجو برای: 1 antitrypsin a1at

تعداد نتایج: 2753541  

Journal: :Clinical and experimental immunology 2008
K Kosai M Seki K Yanagihara S Nakamura S Kurihara Y Imamura K Izumikawa H Kakeya Y Yamamoto T Tashiro S Kohno

Severe pneumonia is found in simultaneous influenza pneumonia and bacterial infection, and suggests a relationship with immunological mechanisms. Here, we performed two-dimensional gel electrophoresis to detect immunological molecules related to the fulminant pneumonia caused by influenza virus and Streptococcus pneumoniae co-infection in mice. We found two spots that were expressed strongly in...

Journal: :Anales de pediatria 2016
B Lara Gallego S Castillo Carullón M T Martínez Martínez M García Reymundo M Miravitlles

Journal: :Pneumologia 2012
Danielius Serapinas Raimundas Sakalauskas

BACKGROUND AND OBJECTIVE Alpha-1 antitrypsin deficiency is an underdiagnosed condition in patients with chronic obstructive pulmonary disease. Diagnosis of this genetic condition is confirmed by genetic verification of pathology, but for screening purposes quantitative methods can be useful. The aim of our study was to evaluate sensitivity and specificity of quantitative methods for alpha-1 ant...

Journal: :Journal of insurance medicine 1988
D J Harris

Alpha-1 antitrypsin deficiency is an inherited disorder that may cause severe lung and liver disease.

Journal: :Thorax 1979
T Sveger P Mazodier

In 11 128 apparently healthy 18-year-old men screened for alpha 1-antitrypsin deficiency (AATD) 44 had an alpha 1-antitrypsin (AAT) level of 50% or less of the transferrin reference. In 42 of the 44 the Pi types were: five Pi Z, 10 Pi SZ, three Pi MZ, one presumptive Pi M-, one Pi FM, and 22 Pi M. Probably all Pi Z and most of the Pi SZ subjects were identified. The transferrin reference, howev...

Journal: :Thorax 1994
N Seersholm A Kok-Jensen A Dirksen

BACKGROUND Previous estimates of the survival times of patients with alpha 1-antitrypsin deficiency have been based on selected patients. METHODS The survival times of 397 patients with severe alpha 1-antitrypsin deficiency identified by pulmonary impairment (index cases) or through family studies (non-index cases) were compared. RESULTS The overall median survival time was 54.5 years with ...

Journal: :Respiratory care 2010
Rachel M Taliercio Robert L Chatburn James K Stoller

BACKGROUND Alpha-1 antitrypsin deficiency is a common genetic condition that predisposes to emphysema and liver disease. Alpha-1 antitrypsin deficiency is under-recognized, so affected individuals often experience long delays in diagnosis and visits to multiple physicians before correct diagnosis. Reasoning that inadequate knowledge about alpha-1 antitrypsin deficiency could contribute to this ...

Journal: :Biotechnology and Bioengineering 2022

The cover image is based on the Article High-level production of wild-type and oxidation-resistant recombinant alpha-1-antitrypsin in glycoengineered CHO cells by Izel Koyuturk et al., https://doi.org/10.1002/bit.28129. Image Credit: Yves Durocher.

2013
Bita Geramizadeh Zahra Jowkar Leila Karami Masoum Masoumpour Samrad Mehrabi Mohammad-Ali Ghayoumi

BACKGROUND Alpha-1 antitrypsin deficiency is a genetic disease which affects both lung and liver. This disease is a recognized factor for chronic obstructive pulmonary disease (COPD). However its importance as the cause of COPD in a country such as Iran is unclear. OBJECTIVES This study was conducted to find out the role of α-1 antitrypsin deficiency as a cause of COPD in Iranian patients. ...

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