We examined multivariate evolution of 20 leaf terpenoids in the invasive plant Melaleuca quinquenervia in a common garden experiment. Although most compounds, including 1,8-Cineole and Viridiflorol, were reduced in home compared with invaded range genotypes, consistent with an evolutionary decrease in defense, one compound (E-Nerolidol) was greater in invaded than home range genotypes. Nerolido...

Cytochrome P450cin (CYP176A1) is a bacterial P450 isolated from Citrobacter braakii that catalyzes the hydroxylation of cineole to (S)-6beta-hydroxycineole. This initiates the biodegradation of cineole, enabling C. braakii to live on cineole as its sole source of carbon and energy. P450cin lacks the almost universally conserved threonine residue believed to be involved in dioxygen activation an...

Neuroprotective Effects of 1,8-Cineole on Apoptosis Inhibition and Bcl-2/Caspase-3 mRNA Expression in the Hippocampus Epileptic Pilocarpine Model Rats

Sir, The emergence of resistance to conventional antimicrobials is a serious problem that physicians face. This necessitates constant development of newer agents, which can inhibit the growth of or kill resistant organisms. Eucalyptus is a tall, evergreen tree, native to Australia and Tasmania, successfully introduced worldwide, now extensively cultivated in many other countries including India...

The suction pipette technique was used to study simultaneously the odour-induced action potential and receptor current responses in frog olfactory receptor cells, which were exposed to the odour cineole for 1 s by rapidly exchanging the solution bathing their cilia. The frequency of action potential firing increased as the odour concentration was raised and saturated within a 15-fold elevation ...

The bovine viral diarrhoea virus (BVDV) is suggested as a model for antiviral studies of the hepatitis C virus (HCV). The antiviral activity of the essential oil of Ocimum basilicum and the monoterpenes camphor, thymol and 1,8-cineole against BVDV was investigated. The cytotoxicities of the compounds were measured by the MTT (3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide) test, a...