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OBJECTIVE To investigate whether luteal E(2) administration reduces size discrepancies of early antral follicles. DESIGN Prospective, crossover study. SETTING ART unit, Clamart, France. PATIENT(S) Sixty women and 120 cycles. INTERVENTION(S) On cycle day 3 (baseline day 3), all women underwent measurements of early antral follicles by ultrasound and serum FSH and ovarian hormones. From d...

Prolonged neutropenia after dose-dense chemotherapy with pegfilgrastim In the dose-dense (DD) chemotherapy trial result reported by Piedbois et al. [1], they found more hematological toxicity leading to treatment discontinuation in the pegfilgrastim supported DD chemotherapy arm. The manufacturer's product information for pegfilgrastim indicates that it should be used once per chemotherapy cycl...

The endocrine and ovarian effects of hypophysectomy (n = 5) and gonadotrophin-releasing hormone (GnRH) antagonist administration (Antarelix) (n = 5) were studied in gilts by comparison with control animals (n = 6). All gilts were given Regumate (20 mg/d for 18 d). The last day of Regumate was day 0. Hypophysectomy and initiation of Antarelix administration (0.6 mg iv twice daily for 7 d) were p...

BACKGROUND AND METHODS Hypertension is a common problem in hemodialysis (HD). However, its behavior during the interdialytic period is not completely known and is infrequently monitored in clinical practice. Thus, for better understanding of interdialytic blood pressure (BP), we analyzed the interdialytic blood pressure profile using 44-hour ambulatory blood pressure monitoring (ABPM) data in 7...