Abstract Study question Could transcriptomic profiling of semen ejaculate be used to predict successful testicular sperm retrieval for men with idiopathic non-obstructive azoospermia (iNOA)? Summary answer Transcriptomic analysis seminal plasma RNA in iNOA revealed gene imbalances that consistently correlated the success retrieving spermatozoa via a biopsy. What is known already Although microd...

Abstract Background Accurate identification of systemic connective tissue diseases (SCTDs) can be challenging due to the heterogeneity each disease. This study aims explore different SCTDs by applying non-supervised learning immunomarker data and proposes an alternative classification. Additionally, investigates clinical implications these groups. Methods We utilized multiple correspondence ana...