nociceptive inputs. Prog Brain Res 1996; 113:525–39 33. Vida G, Peña G, Deitch EA, Ulloa L: 7-cholinergic receptor mediates vagal induction of splenic norepinephrine. J Immunol 2011; 186:4340 – 6 34. Leaders FE, Dayrit C: The cholinergic component in the sympathetic innervation to the spleen. J Pharmacol Exp Ther 1965; 147:145–52 35. Brandon, KW, Rand MJ: Acetylcholine and the sympathetic inner...

In 198 people 201 trampoline injuries are analysed. All except three adults were re-examined, following an observation period of one to four years. School children (145) represented the major part of the 195 persons re-examined. Handling the large trampoline injured 21 of the 145 school children and six children at clubs. Injuries of a permanent nature were found in 49 of the 195 who were re-ex...

Bonnett, R. & Dimsdale, M. J. (1972) J. Chem. Soc. Perkin Trans. 2540-2548 Brown, S. B. & King, R. F. G. J. (1975) Biochem. J. 150, 565-567 Brown, S. B. & King, R. F. G. J. (1976) Biochem. Soc. Trans. 4, 197-201 Jackson, A. H. (1974) in Iron in Biochenlistry andMedicine (Jacobs, A. & Worwood, M., eds.), pp. 145-182, Academic Press, London and New York Schmid, R. (1977) Trans. Assoc. Am. Physici...

12 (1986) p. 1280. 7 Faingold, C.P., Gehlbach, G. and Caspary, D.M., decreased Effectiveness of GABA-Mediated Inhibition in the Inferior Colliculus of the Genetically Epilepsy-Prone Rat., Exp Neurol, 93 (1986) pp. 145-159. 8 Faingold, C.L., Gehlbach, G. and Caspary, n.M., Effects of GABA on inferior colliculus neuronal responses to acoustic stimuli, Society for Neuroscience Abstract, 11 (1985) ...

Inducible cAMP early repressor (ICER) has been shown to be an important mediator of cAMP antiproliferative activity. In this report, it was found that cAMP retards LNCaP cell growth; in contrast, cAMP inhibits the growth of PC-3 and DU-145 cells. ICER protein levels were markedly reduced in prostate cancer epithelial cells and undetectable and uninducible by cAMP in LNCaP and DU 145 cells. Forc...

MicroRNAs are master gene regulators that can also be under the control of transcriptional regulation. We have previously shown that miR-145 is a tumor suppressor capable of silencing c-Myc and the tumor suppressor p53 induces miR-145 by directly binding to the miR-145 promoter, demonstrating the role of miR-145 in p53-mediated c-Myc repression. However, little is known as to why miR-145 is oft...

The present study aimed to investigate the effect of the inhibition of miR-145 on cyclin-dependent protein kinase 6 (CDK6) and the proliferation of human cervical carcinoma cells. The miR-145 sequence was synthesized and cloned into pcDNA™6.2-GW to construct the recombinant plasmid pcDNA6.2-GW-miR-145. HeLa cells were divided into the micro (mi)R-145, normal control and blank groups. The transc...

BACKGROUND The extraordinary invasive capability is a major cause of treatment failure and tumor recurrence in lung cancer. Evidence in other cell systems has implicated the regulatory role of microRNA-145 in cell motility and invasion, which promotes us to investigate the biological functions of miR-145 in lung cancer in this regard. RESULTS We have found that miR-145 is dramatically down-re...