introduction: a cleft lip with or without a cleft palate is one of the major congenital anomalies observed in newborns. this study explored the risk factors for oral clefts in gorgan, northern iran.  materials and methods: this hospital-based case-control study was performed in three hospitals in gorgan, northern iran between april 2006 and december 2009. the case group contained 33 newborns wi...

Ultrasonographic examination is widely used for screening of abnormal findings on prenatal screening. Cleft lip with or without cleft palate of the fetus can also be screened by using ultrasonography. Presence of abnormal findings of the fetal lip or palate can be detected by the imaging professionals. However, such findings may not be familiar to oral and maxillofacial surgeons. Oral and maxil...

To determine quality of life of parents of children with cleft lip and palate and to compare it with parents of non cleft lip and palate children. World Health Organisation Quality of Life (Bref, Field Trial version,1996) for parents of children with cleft lip and palate. Total of 40 parents were questioned , 20 were parents of CLP children and the other 20 were parents of non cleft children. T...

OBJECTIVE This study was performed to analyze features of nasal septal deviation of patients with different cleft types and noncleft controls. STUDY DESIGN Case-control study. SETTING West China Hospital of Stomatology, Chengdu, China. SUBJECTS AND METHODS Sixty-six patients with palatal and/or alveolar cleft and 42 noncleft controls were recruited in the study. All the subjects have unde...

Objective To determine in individuals with unilateral cleft lip and palate the correlation between initial cleft size and dental anomalies, and the outcome of alveolar bone grafting. Methods A total of 67 consecutive patients with non-syndromic unilateral complete cleft lip and palate (UCLP) were included from the cleft lip and palate-craniofacial center, Uppsala University Hospital, Sweden. Al...

In order to assess the association of alleles for candidate genes with non-syndromic cleft lip and palate, DNA samples from 43 Japanese patients were compared with those from 73 control subjects with respect to the genes encoding transforming growth factor alpha (TGFalpha), TGFbeta and gamma-aminobutyric acid type A receptor beta3 (GABRB3). The restriction fragment length polymorphisms of the 3...

OBJECTIVES/HYPOTHESIS To evaluate the prevalence and unmet need for cleft lip-cleft palate reconstructive surgery by using incidence. Our hypotheses were that the age of presentation to screening clinics will decrease between 2006 and 2012, and the geospatial distribution of cases will expand to a more rural catchment area. STUDY DESIGN Longitudinal cross-sectional/geospatial distribution stu...

objective(s:cleft lip/palate are common congenital anomalies, affecting approximately 2/1000 live births. pierre robin sequence is a subgroup of the cleft palate population. chromosomal abnormalities near the sox9 gene disrupt the regulation of this gene and prevent the sox9 protein from properly controlling the development of facial structures, which leads to isolated prs. the present study wa...

OBJECTIVE   To evaluate nasal symmetry using three-dimensional photogrammetry following primary tip rhinoplasty with or without an internal splint in patients with unilateral complete cleft lip/palate. DESIGN   We captured three-dimensional images of patients with unilateral complete cleft lip/palate who underwent nasolabial repair by rotation-advancement of the lip and primary tip rhinoplast...