More VEGF, more life—and health span Advanced aging is celebrated but its ill effects, deterioration at the cell, tissue, and organ levels, are not. Grunewald et al . provide evidence for vascular theory of aging, which reports that age-related decrease function a driver organismal large (see Perspective by Augustin Kipnis). Vascular endothelial growth factor (VEGF) signaling insufficiency unde...

Introduction . Fractures of the maxilla are characterized by such features as close location vital anatomical structures, visual organ, well aesthetic importance this area face and presence risk serious complications. The aim work was to estimate level angiogenic factors in oral fluid: vascular endothelial growth factor A (VEGF-A), D (VEGF-D), placental (PIGF), platelet-derived BB (PDGF-BB) (VE...

Chronic wounds represent a major medical challenge. While the essential role of blood vessel growth and function in wound healing has been thoroughly studied, lymphatic vessels remained unclear. Full-thickness excisional were made wildtype mice, transgenic mice with an increased number cutaneous (K14-VEGF-C expressing lymphangiogenic factor VEGF-C skin), that lack skin (K14-sVEGFR3 soluble form...

Recent research has shown that VEGF may influence the condition and survival of patients with chronic kidney disease (CKD), including those treated dialysis procedures. Identifying value this factor is important to uncover mechanisms CKD progression improve treatment strategies.
 The present study aimed determine mean serum levels vascular endothelial growth (VEGF) its receptor (VEGF-R) th...

Local hyperadrenergic states after a random flap elevation mediated by humoral vasoconstrictors can lead to necrosis. This study aimed evaluate the effect of Botulinum Toxin A (BoNT-A) on reducing levels Norepinephrine (NE) as main vasoactive substance, well its additive with Vascular Endothelial Growth Factor (VEGF) in increasing viability flap. 28 Wistar Rats Caudally Based Modified McFarlane...

introduction: pulsed dye laser (pdl) is an important treatment for superficial infantile hemangioma, but few studies report on its cellular mechanism. the aim of this study was to evaluate alterations of serum vascular endothelial growth factor (vegf) level in infantile hemangioma (ih) patients after laser treatment and effects of pdl irradiation on human umbilical vein endothelial cells (huvec...