Non-proteolytic activities of matrix metalloproteinases (MMPs) have recently been shown to impact cell migration, but the precise mechanism remains to be understood. We previously demonstrated that the hemopexin (PEX) domain of MMP-9 is a prerequisite for enhanced cell migration. Using a biochemical approach, we now report that dimerization of MMP-9 through the PEX domain appears necessary for ...

OBJECTIVE To describe the treatment of polymyositis (PM) and dermatomyositis (DM) with prednisone (PRED) and cyclosporin A (CSA) alone or associated with intravenous immunoglobulin (IVIg) and plasmapheresis (PEX). METHODS Between 1992 and 1999 CSA and PRED were used to treat 20 patients with idiopathic myositis (12 with DM, eight with PM), diagnosed according to the Bohan and Peter criteria. ...

AkzoNobel’s range of organic peroxides for the crosslinking of elastomers and thermoplastics is the world’s largest, including a number of organic peroxides for the production of PEX-a pipes and tubes. Our products are marketed under the well-known trademark of Trigonox. When producing PE pipes and tubes, frequently high density polyethylene (HDPE) is used. To further improve the product proper...

BACKGROUND Bullous keratopathy (BK), a severe sight-threatening disorder can have a variety of etiologies such as prophylactic laser iridotomy, intraocular surgery, trauma, and other ocular disorders. However, there are cases of unknown origins, among which a unique clinical entity namely pseudoexfoliation syndrome (PEX) is having increased importance. CASE PRESENTATION In this case note, we ...

The recent article by Tang et al. [1] supports the idea that Nuss repair improves cardiopulmonary exercise function in teenagers with moderate-to-severe pectus excavatum (PEx). We would like to congratulate the authors for this study and emphasize the relevance of this research, as well as their results, by making some brief remarks. First, the authors circumvented the difficulties in measuring...

هدف: ناباروری یک بحران زندگی است که بیماران را در سراسر جهان تحت تاثیر قرار می دهد، به عنوان عدم موفقیت بارداری پس از 12 ماه فعالیت جنسی تعریف شود 15 تا 17 درصد زوج ها تأثیر دهد و حدود 50 آنها عوامل زنان مربوط شود. فعال کردن روند تقسیم میوز اووسیت بلوغ آن اهداف مهم درمانی محققین علوم بوده است. امروزه القا رشد تکامل خارج بدن یکی روش هایی فنّاوری کمکی تولیدمثل کار گرفته مغز استخوان اندام پیچیده ای...

BACKGROUND Group B Streptococcus (GBS) is a common commensal capable of causing severe invasive infections. Most GBS infections occur in neonates (often as pneumonia). GBS can also cause infection in adults with diabetes and other immunological impairments but rarely leads to pneumonia in adults. GBS has occasionally been found in the sputum of Cystic Fibrosis (CF) patients, an inherited condit...

The following seminar paper is dealing with the recently released new test tool PeX by Microsoft Reseach, which stands short for Program Exploration. The main idea behind it is based on Parameterized Unit Tests, a concept trying to get along with some issues evolving from standard unit tests by supporting the developer with the possibility to let PeX automatically explore the possible execution...

Short title: 1 Plant PEX1 is essential for peroxisomes 2 3 Corresponding author: 4 Bonnie Bartel, Rice University, MS-140, 6100 Main Street, Houston, Texas 77005; Phone: 7135 348-5602; E-mail: [email protected] 6 7 8 9 The PEX1 ATPase stabilizes PEX6 and plays essential roles in peroxisome biology 1 10 11 Mauro A. Rinaldi 2 , Wendell A. Fleming, Kim L. Gonzalez, Jaeseok Park 3 , Meredith J. Ventu...

The evolution of electric vertical takeoff and landing (eVTOL) aircraft as part the Advanced Air Mobility initiative will affect our society environment in fundamental ways. Technological forecasting suggests that commercial services are fast emerging to transform urban regional air mobility for people cargo. However, complexities diverse design choices pose a challenge potential adopters or se...