A binary sequence satisfies a one-dimensional (d; k) run length constraint if every run of zeros has length at least d and at most k. A two-dimensional binary pattern is (d1; k1; d2; k2)-constrained if it satisfies the one-dimensional (d1; k1) run length constraint horizontally and the one-dimensional (d2; k2) run length constraint vertically. For given d1; k1; d2, and k2, the asymmetric two-di...

Grunnet, Morten, Hans-Günther Knaus, Christina Solander, and DanA. Klaerke. Quantification and distribution of Ca21-activated maxi K1 channels in rabbit distal colon. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G22– G30, 1999.—The Ca21-activated maxi K1 channel is an abundant channel type in the distal colon epithelium, but nothing is known regarding the actual number and precise loc...

We recently cloned and characterized the rat kidney-specific organic anion transporter, OAT-K1, which was suggested to mediate renal tubular transport of methotrexate. In this study, we investigated the interactions of nonsteroidal anti-inflammatory drugs (NSAIDs) with OAT-K1 by evaluating the effects of these drugs on renal distribution of methotrexate in vivo, and on methotrexate accumulation...

Murid herpesvirus 4 (commonly called MHV-68) is closely related to Kaposi's sarcoma-associated herpesvirus (KSHV) and provides an excellent model system for investigating gammaherpesvirus-associated pathogenesis. MHV-76 is a naturally occurring deletion mutant of MHV-68 that lacks 9,538 bp of the left end of the unique portion of the genome encoding nonessential pathogenesis-related genes. The ...

BACKGROUND/AIMS In patients with severe acute liver dysfunction, i.v. phylloquinone (vitamin K1) may be given to exclude vitamin K deficiency, rather than impaired hepatic synthesis of coagulation factors alone, as the cause of the coagulopathy. However, there have been no studies of the pharmacokinetics or efficacy of i.v. or oral K1 in such patients. METHODS 49 adults with severe acute live...

This study aimed to investigate whether there is any significant relationship between the readability and vocabulary profile including the most frequent words (K1 words) and academic word list (AWL) of reading passages of Four Corners series which were EFL textbooks. To determine the readability of the texts, the Flesch–Kincaid (1975) readability test was used, while the texts' academic word li...

Li, Dailin, Gary Sweeney, Qinghua Wang, and Amira Klip. Participation of PI3K and atypical PKC in Na1-K1pump stimulation by IGF-I in VSMC. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H2109–H2116, 1999.—The activity of the Na1-K1-pump is intricately linked to the maintenance of vascular tone. Here we demonstrate that insulin-like growth factor I (IGF-I) increases Na1-K1-pump activity in the v...

The inwardly rectifying potassium (Kir) 2.x channels mediate the cardiac inward rectifier potassium current (I(K1)). In addition to differences in current density, atrial and ventricular I(K1) have differences in outward current profiles and in extracellular potassium ([K+]o) dependence. The whole-cell patch-clamp technique was used to study these properties in heterologously expressed Kir2.x c...

سابقه و هدف: جنگل­ های زاگرس به ­عنوان یکی از بوم ­سازگان­ جنگلی مهم ایران پوشش­ گیاهی (درختان، درختچه ­ها گونه­ علفی) متنوعی برخوردار می­ باشد. شناسایی آگاهی دقیق نقش ­شناختی آنها در این ­سازگان تواند حفاظت منابع طبیعی توسعه پایدار کمک شایانی نماید. به‌منظور مطالعه تنوع گونه‌ای گیاهان چوبی ذخیره کربن خاک رابطه با عوامل فیزیوگرافیک (جهت، شیب ارتفاع سطح دریا)، رویشگاه کیکم (var. cinerascens Acer...