during the era of bush administration and post-september 11th anti-terrorism discourse, the movie 300 was one of the best exemplar of a close relationship between hollywood pop culture products and the neo-conservatives’ political discourse of nationalism. from my point of view, 300 is not an example of outstanding artistic films, but a film that more than any other film contains an iranophobic...

Atazanavir/ritonavir (ATV/r) 200/100 mg once-daily (OD) has been shown comparable in drug exposure to the standard dose in Asian study. We explored the pharmacokinetic profiles of the boosting effect of ritonavir at 50 mg to either atazanavir 300 or 200 mg in 32 adult Thai healthy volunteers. The geometric means (GM) of ATV AUC0-24 were 40.66, 25.50 and 24.97 mg-h/L and Cmin were 0.53, 0.27 and...

The interaction between dl-sotalol and isoproterenol on the ventricular effective refractory period (VERP) and conduction were examined in an electrophysiologic study of 9 patients at drug-free baseline, after 14 days of dl-sotalol administration (320 mg/day), and after the administration of isoproterenol. In all 9 patients, ventricular tachyarrhythmia could not be induced after dl-sotalol trea...

The experiment was conducted to investigate the effects of dihydropyridine on laying performance and fat metabolism of laying hens. Five hundred and forty laying hens, 40 weeks old, were randomly allotted to three groups, each of which included four replicates of 45 hens. The groups were given a basal corn-soybean meal diet supplemented with 0, 150 mg/kg and 300 mg/kg dihydropyridine. Results s...

Randomized participants (n = 811) had amean (SD) HbA1c of 8.24% (0.82) and BMI of 34.8 kg/m (6.4). Glycemic control improved similarly with both basal insulins; least squares mean (SD) reduction from baseline was 20.57% (0.09) for Gla-300 and20.56% (0.09) for Gla-100 (mean difference20.01% [95% CI20.14 to 0.12]), with 10% higher dose of Gla-300. Less nocturnal confirmed (£3.9 mmol/L [£70 mg/dL]...

In the course of our screening for compounds that reverse multidrug resistance, we found that the cytotoxicity of vincristine was enhanced 1.5-20-fold depending on the concentration of andrastin A in vincristine-resistant KB cells (VJ-300). Andrastin A alone had no effect on the growth of drug sensitive KB cells and VJ-300 cells. On the other hand, andrastin A (25 and 50 micrograms/ml) signific...