We describe an integrated approach for detection of diagnostic markers using in situ assembled optical diffraction gratings in combination with immunomagnetic capture. Folate receptor (FR), a serum protein indicative of various cancers, was chosen as a model system to demonstrate the potential of the method. Magnetic beads coupled to FR antibody were used to capture FR from serum. The FR-bound ...

A suitable measure for the similarity of shapes represented by parameterized curves or surfaces is the Fr echet distance. Whereas e cient algorithms are known for computing the Fr echet distance of polygonal curves, the same problem for triangulated surfaces is NP-hard. Furthermore, it remained open whether it is computable at all. Using a discrete approximation we show that it is upper semi-co...

RATIONALE AND OBJECTIVE Receptor-targeted delivery of imaging and therapeutic agents can lead to enhanced efficacy for both. Multimodality imaging offers unique advantages over traditional single modality imaging. Tumor marker folate receptor (FR)-targeted fluorescent paramagnetic bimodal liposomes were synthesized to co-deliver paramagnetic and fluorescence agents for magnetic resonance (MR) a...

one of the important issues in hydraulic engineering is inspection of local scour depth around bridge pier. using piles is one of the ways for confronting local scour and erosion. in this study, the experiments were conducted in an 8m long, 0.5m deep and 0.25m wide flume. and the effectof using piles and number of them observed on the amount of scour in three different frude numbers. the shape ...

The degree of nutrient enhancement during the newborn period may modulate programming of appetite-regulating hormones, body composition, and propensity to adult obesity in intrauterine growth-restricted (IUGR) newborns. Pregnant rats received, from day 10 to term gestation and throughout lactation, ad libitum food (AdLib) or 50% food restriction (FR) to produce IUGR newborns. AdLib vs. FR offsp...

Dynamic balance ability related to maintaining postural stability during movement is closely tied to fall risk in the elderly. The functional reach (FR) test has been developed to evaluate their dynamic balance. Although a simple and new FR test using an elastic stick has been proposed by modifying the above original FR test, the abilities related to both FR tests are judged to differ because o...

Objectives: Cerebral Palsy (CP) is a non-progressive brain damage that leads to movement and balance disorders. One of the new rehabilitation approaches for such children is Kinesio taping. The present study aimed to investigate the effect of lower limbs kinesio taping on static and dynamic balance in children with CP. Methods: In this pilot randomized clinical trial, 30 children with CP were ...

Apolipoprotein E (apoE) in high density lipoprotein (HDL) fraction (HDL-fr) was determined by the immunofixation method and turbidimetric immunoassay (TIA) after precipitation with phosphotungstic acid/MgCl2 in normolipidemic control subjects and patients with type IV hyperlipemia and hyper HDL-cholesterolemia. Immunofixation assay revealed two major bands of apoE in whole serum: one in the alp...

Algorithms for planning quasistatic attitude maneuvers based on the Jacobian of the forward kinematic mapping of fully-reversed (FR) sequences of rotations are proposed in this paper. An FR sequence of rotations is a series of finite rotations that consists of initial rotations about the axes of a body-fixed coordinate frame and subsequent rotations that undo these initial rotations. Unlike the...