The aim of this study was to assess the prevalence of malocclusion in Benin City. A total of 441 school children, 229 males and 212 females of mean age 13.52 years ± 1.83 who had no previous history of orthodontic treatment were assessed for occlusal, space and dental anomalies. Angle's classification was used to assess buccal sagittal relationships. The results showed that 15.9% of the subject...

to report the oral findings, including dental anomalies, ectopic eruption of the maxillary permanent first molars and periodontal disease and soft tissue alterations, in a subject with apert syndrome. clinical and radiographic examination of a patient with apert syndrome, aged 21 years old, not previously submitted for orthodontic or orthognathic treatment. dental anomalies were present in a pa...

OBJECTIVE Given the considerable disagreement between the Peer Assessment Rating (PAR) index and the American Board of Orthodontics Cast-Radiograph Evaluation, we aimed to develop a novel assessment system-the Improvement and Completion of Outcome (ICO) index-to evaluate the outcome of orthodontic treatment. METHODS Sixteen criteria from 4 major categories were established to represent the pr...

Abstract Bispecific T cell engager (BiTE) is one of the most promising therapeutic approaches for treatment various malignancies. Humanized mice engrafted with human peripheral blood mononuclear cells (PBMCs) have currently become preclinical platform evaluating effectiveness cancer immunotherapies including BiTE. However, wide application this humanized animal model limited by a strong xenorea...