BACKGROUND Transcatheter aortic valve implantation (TAVI) has emerged as an acceptable treatment modality for patients with severe aortic stenosis who are deemed inoperable by conventional surgical aortic valve replacement (AVR). However, the role of TAVI in patients who are potential surgical candidates remains controversial. METHODS A systematic review was conducted using five electronic da...

Thrombosis is a prominent feature of acute vascular rejection (AVR), the current barrier to survival of pig-to-primate xenografts. Fibrinogen-like protein 2 (fgl2/fibroleukin) is an inducible prothrombinase that plays an important role in the pathogenesis of fibrin deposition during viral hepatitis and cytokine-induced fetal loss. We hypothesized that induction of fgl2 on the vascular endotheli...

BACKGROUND Current guidelines generally recommend watchful waiting until symptoms emerge for aortic valve replacement (AVR) in asymptomatic patients with severe aortic stenosis (AS). OBJECTIVES The study sought to compare the long-term outcomes of initial AVR versus conservative strategies following the diagnosis of asymptomatic severe AS. METHODS We used data from a large multicenter regis...

OBJECTIVES Aortic valve replacement (AVR) with sutureless bioprostheses has become an alternative to conventional AVR for patients with intermediate to high operative risk. However, this technique is associated with an increased risk of postoperative conduction disorders. METHODS We analysed 258 patients who underwent AVR with the Perceval prosthesis from July 2010 to September 2014 at our ce...

AIM This study evaluated the prognostic implications of aVR ST elevation during ST elevation acute myocardial infarction (AMI). METHODS AND RESULTS The Hirulog and Early Reperfusion/Occlusion-2 study randomized 17 073 patients with acute ST elevation AMI within 6 h of symptom onset to receive either bivalirudin or heparin, in addition to streptokinase and aspirin. The treatments had no effect...

This paper presents performance of intelligent fuzzy-based coordinated control for Automatic Voltage Regulator (AVR) and Power System Stabilizer (PSS), to prevent losing synchronism after major sudden faults and to achieve appropriate post-fault voltage level in multi-machine power systems. The AVR and PSS gains can adaptively change to guarantee the power system stability after faults. For cha...

Background Aortic valve replacement (AVR) is the definitive treatment for severe symptomatic aortic stenosis (AS). Aortic stenosis is associated with diastolic dysfunction and left atrial (LA) enlargement. After a successful AVR, there is a decrease in LA size but persistence in diatolic dysfunction. We hypothesized that LA function would help link this discordance. Cardiac magnetic resonance (...

This paper presents the robust design of a Power System Stabilizer (PSS) to improve the stability in the composed two-area Load Frequency Control (LFC) and Automatic Voltage Regulator (AVR) using Artificial Bee Colony (ABC) in a restructured environment. The coupling effects of the LFC and AVR loops are studied by extending the linearized Automatic Generation Control (AGC) system to include the...

BackgroundLong-term outcomes of aortic valve replacement (AVR) are worse in patients with tricuspid regurgitation (TR), but the impact concomitant intervention remains unclear. The purpose this study was to determine effect TR undergoing AVR.MethodsPatients AVR a regional Society Thoracic Surgeons database (2001-2017) were stratified by severity and whether or not they underwent intervention. O...

BACKGROUND Severe pulmonary arterial hypertension in patients with severe aortic stenosis (AS) carries a poor prognosis. There are limited data on the effect of aortic valve replacement (AVR) in these patients. METHODS Our echocardiographic database between 1993 and 2003 was searched for patients with severe AS defined as a Doppler estimated aortic valve area of 0.8 cm2 or less and severe pul...