SR-BI deficient mice that are also hypomorphic for apolipoprotein E expression develop diet induced occlusive coronary artery atherosclerosis, myocardial infarction and early death. To test the role of SR-BI in bone marrow derived cells, we used bone marrow transplantation to generate SR-BI-null; apoE-hypomorphic mice in which SR-BI expression was restored solely in bone marrow derived cells. S...

Scavenger receptor, class B, type I (SR-BI) is a cell-surface glycoprotein that mediates selective uptake of high density lipoprotein cholesteryl ester (CE) without the concomitant uptake and degradation of the particle. We have investigated the endocytic and selective uptake of low density lipoprotein (LDL)-CE by SR-BI using COS-7 cells transiently transfected with mouse SR-BI. Analysis of lip...

Species diversity, richness and biomasses (aboveground biomass) and their relationships are the key variables of ecosystems. This study was conducted to determine the relationship of Species Diversity (SD) and Species Richness (SR) with Above-Ground Biomass (AGB) at a local scale at 5 different habitats (shrubland, forbland, grassland, shrub-forbland and forb-shrubland) in Zagros mountains in w...

The scavenger receptor class B type I (SR-BI), which is expressed in the liver and intestine, plays a critical role in cholesterol metabolism in rodents. While hepatic SR-BI expression controls high density lipoprotein (HDL) cholesterol metabolism, intestinal SR-BI has been proposed to facilitate cholesterol absorption. To evaluate further the relevance of SR-BI in the enterohepatic circulation...

Given a family F of r-graphs, let ex(n,F) be the maximum number of edges in an n vertex r-graph containing no member of F . Let C 4 denote the family of r-graphs with distinct edges A,B, C, D, such that A ∩ B = C ∩ D = ∅, A ∪ B = C ∪ D. For s1 ≤ · · · ≤ sr, let K(s1, . . . , sr) be the complete r-partite r-graph with parts of sizes s1, . . . , sr. Füredi conjectured over 15 years ago that ex(n,...

Although Ca(2+)/calmodulin-dependent protein kinase-II (CaMK) is known to phosphorylate different Ca(2+) cycling proteins in the cardiac sarcoplasmic reticulum (SR) and regulate its function, the status of CaMK in heart failure has not been investigated previously. In this study, we examined the hypothesis that changes in the CaMK-mediated phosphorylation of the SR Ca(2+) cycling proteins are a...

The aim of this study was to assess the effects of stochastic resonance (SR) stimulation on sensorimotor performance during an episode of exercise-induced muscle damage (EIMD). Thirty four men (age: 21.3 (±2.6) years; height 1.78 (±0.06) m; body mass 72.3 (±7.4) kg (mean (±SD)) gave their informed consent to participate in this study.Sensorimotor performance (error in replicating a target force...

The ultralong strontium- (Sr-) substituted hydroxyapatite (SrHAp) whiskers were successfully prepared using acetamide as homogeneous precipitation reagent. The effect of the Sr substitution amount on the lattice constants and proliferation of human osteoblast cells (MG-63) was further investigated. The results showed that the SrHAp whiskers with diameter of 0.2-12 μm and ultralong length up to ...

This study examined the food intake changes evoked by intracerebroventricular (icv) injection of a selective agonist (BRL37344, 2 and 20 nmol) or antagonist (SR59230A, 10 and 50 nmol) of β3-adrenergic receptors in 24-h fasted rats (adult male Wistar rats, 200-350 g, N = 6/treatment). The animals were also pretreated with saline icv (SAL) or SR59230A (50 nmol) followed by BRL37344 (20 nmol) or S...

Scavenger receptor class B type I (SR-BI) is a high-density lipoprotein receptor that regulates cholesterol efflux from the peripheral tissues to the liver. SR-BI has been identified on astrocytes and vascular smooth muscle cells in Alzheimer's disease brain and has been shown to mediate adhesion of microglia to fibrillar amyloid-β (Aβ). Here we report that SR-BI mediates perivascular macrophag...