This paper formulates a set of minimal requirements for the Platform Independent Model (PIM) of the Model Driven Architecture (MDA). It then defines the Use Case, Responsibility Driven Analysis and Design methodology (URDAD) which provides a simple, algorithmic design methodology generating a PIM satisfying the specified PIM requirements. 2008 Elsevier B.V. All rights reserved.

BACKGROUND Multimorbidity and polypharmacy represent a major problem for elderly patients. Potentially inappropriate medication (PIM) use is highly prevalent among the elderly. PIMs are considered high-risk drugs and are suspected to be responsible for adverse drug events (ADEs) leading to hospitalization. OBJECTIVE The objective of this study was to determine hospitalization rates related to...

AIM To compare estimates of unplanned hospitalizations associated with exposure to Beers potentially inappropriate medications (PIM) in elderly people receiving different levels of ongoing general practitioner (GP) care. METHODS Using the pharmaceutical claims and other linked health data of 245,436 Western Australians aged ≥65 years with one or more claims for a medication from a PIM-related...

OBJECTIVE To follow proinsulin immunoreactive material (PIM) in healthy siblings from the time of diagnosis of insulin-dependent diabetes mellitus (IDDM) in the proband, for at least 2 years. DESIGN AND METHODS The study comprised 148 siblings representing 112 families. The siblings were recruited from the nationwide 'Childhood Diabetes in Finland' study and tested for immunological markers. ...

This paper discusses the potential use of Processing-InMemory (PIM) Technology in petaflops level computing. It starts with a quick review of a proposed PIM architecture called Shamrock, and follows that up with a discussion of several execution models that the architecture supports. Sizings for a petaflops-level machine constructed solely from PIM devices at several points in time are given. T...

Another component in Pattern-Oriented and ModelDriven Architecture (POMA) [1] is the concept of model transformation. The transformation of models is the process of creating a model from another model using transformation rules. In this paper, we present the transformation rules that enable to transform the five PIM models between them and also the five PSM models. These different PIM and PSM m...

We present a generic wide-field optical sectioning scheme, photobleaching imprinting microscopy (PIM), for depth-resolved cross-sectional fluorescence imaging. Wide-field PIM works by extracting a nonlinear component that depends on the excitation fluence as a result of photobleaching-induced fluorescence decay. Since no specific fluorescent dyes or illumination modules are required, wide-field...

Personal epistemology and information management activity can deeply affect each other; the links between them are attracting more and more attention. By comparing with the organizational information management, the connections between PIM (personal information management) and PKM (personal knowledge management) are analyzed. Based on the development of PIM, a new personal epistemology model is...

Constraints play a key role in the definition of conceptual schemas. In the UML, constraints are usually specified by means of invariants written in the OCL. However, due to the high expressiveness of the OCL, the designer has different syntactic alternatives to express each constraint. The techniques presented in this paper assist the designer during the definition of the constraints by means ...

This study presents a systematic methodology for MDA transformation that includes creating a platform independent model (PIM), transforming PIM into platform specific model (PSM), and transforming PSM into a Code model. The PIM is created first based on the use case, activity diagram and robustness diagram. The PIM is then transformed into a PSM based on three target platforms: Web-based user i...