Heparin has been conventionally used as an anticoagulant for medical and surgical indications. Because factor Xa is an essential component of the prothrombinase complex and leads to the generation of thrombin, its inhibition has become a focus of newer antithrombotic drug development. The in vitro anticoagulant profile of DX-9065a, a synthetic direct factor Xa inhibitor, was studied using activ...

Objective To evaluate the performance of dual internally cooled wet tip (ICWT) radiofrequency electrodes in comparison to (ICT) electrodes.Methods Twenty ablation zones were created for each type electrodes. Planned procedure time was 6 min. Diameters zone along x-, y-, and z-axes (Dx, Dy, Dz), sphericity, quantitative sphericity measurement, volume measured compared between two electrode types...

Motivated by a recent study of Bessel operators in connection with refinement Hardy's inequality involving $ 1/\sin^2(x) on the finite interval (0, \pi) $, we now take closer look at underlying Bessel-type more general inverse square singularities endpoints. More precisely, consider quadratic forms and operator realizations L^2((a, b); dx) associated differential expressions form \begin{documen...

OBJECTIVE In patients with unilateral vesicoureteral reflux (VUR), it has been suggested that injection of a non-refluxing but cystoscopically abnormal contralateral ureteral orifice (UO) with dextranomer/hyaluronic acid (Dx/HA) should be performed to prevent the development of de-novo contralateral VUR. We evaluate the effectiveness of this practice. PATIENTS AND METHODS Patients with primar...

One of the main objectives of the Transition Radiation Detector (TRD) at LHC at CERN is to provide electron/pion identification for pt > 1GeV/c. The separation of electrons is based on ionization dE/dx and TR production and detection. We have improved the electron identification by better considering the contributions of ionization and TR production on the dE/dx measurements. The TRD detector d...

Let X = {Xt, t ∈ R+} be a symmetric Lévy process with local time {Lt ; (x, t) ∈ R × R +}. When the Lévy exponent ψ(λ) is regularly varying at zero with index 1 < β ≤ 2, and satisfies some additional regularity conditions, lim t→∞ ∫∞ −∞(L x+1 t − Lt ) dx− E (∫∞ −∞(L x+1 t − Lt ) dx ) t √ ψ−1(1/t) L = (8cψ,1) 1/2 (∫ ∞ −∞ ( Lβ,1 )2 dx )1/2 η, where Lβ,1 = {Lβ,1 ; x ∈ R} denotes the local time, at ...

The respiratory gas exchange and ventilation during an incremental cycle exercise test were analysed in a group of 19 healthy, moderately fit men. Different computer algorithms were used to estimate the VO2 values where: (i) the rate of VCO(2) increase just exceeds the rate of VO(2) increase (DX, derivative crossing), (ii) VCO(2)/VO(2) = 1.00 (PX, point of crossing) and (iii) ventilation (VE) i...

If B is an infinite subset of ω and X is a topological group, let CX B be the set of all x ∈ X such that 〈xn : n ∈ B〉 converges to 1. If F is a filter of infinite sets, let DX F = ⋃{CX B : B ∈ F}. The CX B and DX F are subgroups of X when X is abelian. In the circle group T, it is known that CX B always has measure 0. We show that there is a filter F such that DT F has measure 0 but is not cont...

We study the role played by the indefinite weight function a(x) on the existence of positive solutions to the problem  −div (|∇u|∇u) = λa(x)|u|u+ b(x)|u|u, x ∈ Ω, ∂u ∂n = 0, x ∈ ∂Ω , where Ω is a smooth bounded domain in Rn, b changes sign, 1 < p < N , 1 < γ < Np/(N − p) and γ 6= p. We prove that (i) if ∫ Ω a(x) dx 6= 0 and b satisfies another integral condition, then there exists some λ∗ suc...

The endoscopic injection of Dx/HA in the management of vesicoureteral reflux (VUR) has become an accepted alternative to open surgery. In the current study we evaluated the value of cystography to detect de novo contralateral VUR in unilateral cases of VUR at the time of Dx/HA injection and correlated the findings of immediate post-Dx/HA injection cystography during the same anesthesia to 2-mon...