Cloud computing datacenters provide millions of virtual machines in actual cloud markets. In this context, Virtual Machine Placement (VMP) is one of the most challenging problems in cloud infrastructure management, considering the large number of possible optimization criteria and different formulations that could be studied. In the existing literature, the VMP problem is mostly formulated as a...

To assess the time-varying dynamics in value-at-risk (VaR) estimation, this study has employed an integrated approach of dynamic conditional correlation (DCC) and generalized autoregressive heteroscedasticity (GARCH) models on daily stock return emerging markets. A log-returns three leading indices such as KSE100, KSE30, KSE-ALL from Pakistan Stock Exchange SSE180, SSE50 SSE-Composite Shanghai ...

این پژوهش با الهام گرفتن از نتایج یک طرح مطالعاتی کاربردی، رویکرد سلسله­‌مراتبی جهت پیگیری فرایند توسعه تأمین‌کنندگان و حمایت تصمیمات موجود در هر مراحل آن ارائه‌ می‌کند. ابتدا، زمینه‌های تأمین نیازمند سپس واجد شرایط هریک زمینه‌ها به کمک تصمیم‌گیری چندشاخصه بهترین-بدترین مشخص می‌گردند. معیارهای شناسایی نیز مرور مطالعات پیشین بهره‌گیری نظرات خبرگان حوزه‌ی خرید استخراج‌شده‌اند. درنهایت، مدل ریاضی ...

Double Data Rate Dynamic Random Access Memory (DDR DRAM) has become important to develop a low-power high performance DCC(Duty Cycle Corrector) with better duty cycle accuracy. DDR DRAM increases the speed using Successive Approximation Register Duty Cycle Corrector (SAR DCC). The proposed DCC circuit will be implemented in a 0.18um CMOS process. Here, Adjuster circuit delay line is being modif...

AIM To investigate the role of DCC gene inactivation in the development and progression of gastric cancer. METHODS Loss of heterozygosity and loss of expression of the DCC gene was studied in 51 surgical specimens of gastric cancer using detection based on polymerase chain reaction. RESULTS Loss of heterozygosity was found in 35.3% (18 of 51) of specimens and was detected more often in stag...

To achieve X-chromosome dosage compensation, organisms must distinguish X chromosomes from autosomes. We identified multiple, cis-acting regions that recruit the Caenorhabditis elegans dosage compensation complex (DCC) through a search for regions of X that bind the complex when detached from X. The DCC normally assembles along the entire X chromosome, but not all detached regions recruit the c...

Paranodal axoglial junctions are essential for the segregation of myelinated axonsinto distinct domains and efficient conduction of action potentials. Here, we show thatnetrin-1 and deleted in colorectal cancer (DCC) are enriched at the paranode in CNSmyelin. We then address whether netrin-1 signaling influences paranodal adhesionbetween oligodendrocytes and axons. In the absenc...

Netrin-1 modulates axonal growth direction and speed. Its best characterized receptor, Deleted in Colorectal Cancer (DCC), is localized to growth cones, but also observed in the cell bodies. We hypothesized that cell bodies sense Netrin-1 and contribute to axon growth rate modulation, mediated by the second messenger system. We cultured mouse cortical neurons in microfluidic devices to isolate ...