reports dealing with the higher affinity of Hp 2-2, compared with Hp 1-1, for the CD163 receptor on macrophages. The more efficient uptake of the multimeric Hp molecules is reflected in the serum concentrations of free Hb. The observed differences in free Hb between Hp phenotypes could help to explain the previously reported differences in oxidative stress markers among Hp phenotypes (3, 10). I...

The combination of nanoparticles and biological molecules is of intense interest because of the synergistic properties offered by such newly synthesized composites. Heparin (HP), conjugated to nanomaterials, has recently been investigated for its chemical and biological properties. HP has a number of biological activities that can be enhanced when composited with nanoparticles. In addition, HP ...

In vitro observations suggest a role for the mouse heterochromatin protein 1γ (HP-1γ) in the immune system. However, it has not been shown if and how HP-1γ contributes to immunity in vivo. Here we show that in mice, HP-1γ positively regulates the germinal center reaction and high-affinity antibody response to thymus (T)-dependent antigens by limiting the size of CD8(+) regulatory T-cell (Treg) ...

We let Harrington’s Principle, HP, denote the statement that there is a real x such that every x–admissible ordinal is a cardinal in L. Harrington’s proof of “Det(Σ1) implies 0 ] exists” in ZF is done in two steps: first show that Det(Σ1) implies HP and secondly show that HP implies 0 ] exists. We observe that the first step is provable in Z2. In this paper we prove via class forcing that Z2 + ...

1 AP-HP, Hôpital Armand Trousseau, Service de Neuropédiatrie, Paris, France 2 UPMC Univ Paris 06, Paris, France 3 CHU d’Angers, Département de Biochimie et Génétique, Angers, France 4 UMR CNRS 6214—INSERM 771, Angers, France 5 AP-HP, Hôpital Bicêtre, Laboratoire de Biochimie, Paris, France 6 AP-HP, Hôpital Armand Trousseau, Service de Chirurgie Orthopédique et du Neurohandicap, Paris, France 7 ...

1 Equipe "VIH et IST", Centre de Recherche en Epidémiologie et Santé des Populations (CESP), INSERM U1018; Univ Paris-Sud 11, Faculté de Médecine; Service d’Epidémiologie et de Santé Publique, Hôpital Bicêtre, AP-HP, Le Kremlin Bicêtre, France 2 Service de Médecine Interne, Hôpital Bicêtre, AP-HP, Le Kremlin Bicêtre, France 3 Centre de Diagnostic et de Thérapeutique, Hôpital Hôtel Dieu, AP-HP, ...

background: helicobacter pylori (hp) is a gram negative, spiral shaped bacterium which colonizes the gastric mucosa and induces gastroduodenal complications varying from mild gastritis with no clinical complications to peptic ulcer diseases and even gastric malignancies. the rate of hp infection is 30-50% in developed countries whereas it has been rated up to 80% of the adult population in deve...

BACKGROUND Disadvantaged groups are often not reached by mainstream health promotion interventions. Implementing health promotion (HP) interventions in social economy companies, can be an opportunity to reach those people. The implementation of these interventions in social economy companies was studied. Factors that could be related to the implementation of HP and being supportive towards impl...

54 patients (22 females, 32 males, age 21-79, mean 45 years) referred for upper gastrointestinal endoscopy were investigated. Helicobacter pylori (HP) infection was determined using histology (H&E and Giemsa stain), rapid urease test (CLO) and serology (Cobas Core Anti-H. pylori EIA). Density of HP colonization was determined in gastric antral (3 biopsy specimens) and body mucosa (2 biopsy spec...

AIM To determine gastric tissue lactoferrin (Lf) levels of Helicobacter pylori- (Hp-) positive and -negative patients and its effect on anemia. METHODS Cases in which initial presentation was of abdominal pain and that were Hp-positive at endoscopy were included. Hp-positive cases and -negative controls were divided into two groups. RESULTS The study included 64 cases (average: 10.2 ± 0.4 y...