We use the Taylor-Wiles-Kisin patching method to investigate multiplicities with which Galois representations occur in mod $\ell$ cohomology of Shimura curves over totally real number fields. Our relies on explicit computations local deformation rings done by Shotton, we compute Weil class group various rings. Exploiting natural self-duality groups, these precisely determine structure a patched...

Maternal hypertension associated with renal disease is a common pregnancy complication. Previously, we have shown in a rabbit model of mild hypertension that offspring from hypertensive mothers have increased blood pressure as adults. In human pregnancy, hypertension has been associated with decreased utero-placental blood flow. The aim of this study was to determine placental blood flow (PBF) ...

The issue of whether the signaling process during positive selection can affect the efficiency by which the positively selected T cells respond to antigenic stimulation has not been addressed. We approached this question by determining the consequences of positive selection of a particular transgenic TCR (2C TCR) in the H-2b and the H-2k thymus. The H-2b thymus provides a strong positive-select...

BACKGROUND This study aimed to explore the effect of baicalin, which is a kind of bioactive flavonoid, on blood pressure and left ventricular remodeling in rats with renovascular hypertension. MATERIAL AND METHODS A total of 40 male Wistar rats were randomly assigned into sham-operation (n=10) and renal hypertension model groups (2-kidney-1 clip; 2K-1C, n=30). The rats in the renal hypertension...

We address the question of the maximum number ex(m,n, C2k) of edges in an m by n bipartite graph without a cycle of length 2k. We prove that for each k ≥ 2, ex(m,n, C2k) ≤    (2k − 3) [ (mn) k+1 k + m + n ] if k is odd. (2k − 3) [ m k+2 k n 1 2 + m + n ] if k is even.

Pancreatic ductal adenocarcinoma is one of the lethal cancers with extensive local tumour invasion, metastasis, early systemic dissemination and poorest prognosis. Thus, understanding the mechanisms regulating invasion/metastasis and epithelial-mesenchymal transition (EMT), is the key for developing effective therapeutic strategies for pancreatic cancer (PaCa). Eukaryotic elongation factor-2 ki...