Folic acid (FA) and doxorubicin (DOX) are coupled separately onto Fe3 O4 @SiO2 and polystyrene surfaces of a unique polystyrene/Fe3 O4 @SiO2 Janus structure. This super-paramagnetic, dual-functionalized Janus nanocomposite enables effective tumor cell targeting and internalization via the folate receptor, and induces significant cancer cell death by controlled, stimulus-induced drug release und...

An anisotropic product angular distribution has been observed in the dissociative photodetachment of O4 2 at 523 nm. Energy and angular distributions of coincident O2 products from the process O4 1hn→O21O21e were measured using translational energy spectroscopy in a fast ion beam. The angular distribution peaks perpendicular to the electric vector of the laser beam. © 1995 American Institute of...

The infrared and Raman spectra of Ce2(WO4)3 and La2(WO4)3, which are complicated by the superposition of bands from two non-equivalent WO4 units, have been successfully assigned above 300 cm −1 according to Td point group symmetry. Individual assignment of the two types of tungstate units, WO4 (C2 site symmetry) and W O4 (C1 site symmetry), relies on comparison with the spectra of tetrahedral r...

Formation and accumulation of O6-alkylguanine and O4-alkylthymine in human tissues is possibly the most relevant marker for cancer risk. Because humans are chronically exposed to diverse kinds of chemicals and eventual DNA structural modifications are supposed to be a complex mixture of adducts at very low levels, it is essential to use an assay with extremely high sensitivity and specificity. ...

Serotyping is widely used for typing Salmonella during surveillance, and depends on determining the lipopolysaccharide (LPS) O-antigen and the flagellar protein (H-antigens) components. As the O-antigen is highly variable, and structurally unique to each serotype, we investigated the binding affinities of LPS from Salmonella serotypes of O4 serogroup with specific anti-antigen serum via immunob...

O2-Ethyl-UDP and O4-methyl-UDP have been prepared and copolymerized in various proportions with UDP or CDP, using polynucleotide phosphorylase. The copolymers were used as templates for DNA-dependent RNA polymerases in the presence of Mn2+. Both of the O-alkylated uridines caused a similar misincorporations. When copolymerized with U they led to incorporation of CMP and GMP into the poly(A). No...

The alkali-metal ion extraction ability of an inert material, polytetrafluoroethylene (PTFE; empirical formula CF2), was clarified by characterizing a partially alkali-metal ion-extracted layered compound, K0.8(Li0.27Ti1.73)O4. Washing K0.8(Li0.27Ti1.73)O4 in water extracts only 44% of the interlayer K(+) and no intralayer Li(+); on the other hand, 53% of the interlayer K(+) and approximately 1...

Spinel oxides of Li[LiyTi2-y]O4 with 0 ≤y≤ 1/3 exhibit two desirable features for solid state chemistry and condensed matter physics. One is a reversible lithium insertion/extraction reaction, in particular for Li[Li1/3Ti5/3]O4, and the other is a superconducting transition at Tc≃ 13 K for Li[Ti2]O4. To study the change in magnetic environments of the y = 1/3 compound with excess Li(x), we meas...