BACKGROUND AND OBJECTIVE We aimed to assess the validity of using the Global Lung Function Initiative's (GLI) 2012 equations to interpret lung function data in a healthy workforce of South Australian Metropolitan Fire Service (SAMFS) personnel. METHODS Spirometry data from 212 healthy, nonsmoking SAMFS firefighters were collected and predicted normal values were calculated using both the GLI ...

RATIONALE There is no consensus as to when treatment for idiopathic pulmonary fibrosis (IPF) should be initiated. Some physicians prefer not to treat patients with preserved lung volume. OBJECTIVE To investigate whether patients with IPF and preserved lung volume receive the same benefit from nintedanib as patients with more impaired lung volume. METHODS Post hoc subgroup analyses of pooled...

STUDY OBJECTIVE To assess the restrictive effects of two spinal immobilization strapping techniques on the respiratory capacity of normal, healthy children. DESIGN Prospective study with each subject serving as his own control. PARTICIPANTS Fifty-one healthy children 6 to 15 years old. INTERVENTIONS Participants' forced vital capacity (FVC) measurements were first obtained with children s...

Objectives: This study was aimed to determine the Effect effect of incentive spirometry on pulmonary function tests in patients undergoing hemodialysis. Methods: This study was a randomized clinical trial conducted in on hemodialysis patients. The obtained Data were collected from 26 patients in the experimental and 26 patients in the control group. In The the control group, patients received ...

PURPOSE Airway remodeling may be responsible for irreversible airway obstruction in asthma, and a low post-bronchodilator FEV1/FVC ratio can be used as a noninvasive marker of airway remodeling. We investigated correlations between airway wall indices on computed tomography (CT) and various clinical indices, including post-bronchodilator FEV1/FVC ratio, in patients with asthma. METHODS Volume...

BACKGROUND MicroRNAs are key transcriptional and network regulators previously associated with asthma susceptibility. However, their role in relation to asthma severity has not been delineated. OBJECTIVE We hypothesized that circulating microRNAs could serve as biomarkers of changes in lung function in asthma patients. METHODS We isolated microRNAs from serum samples obtained at randomizati...

The fractional vegetation coverage (FVC) can visually represent ecological changes in a region. Based on MDO12A1 data to calculate FVC, we investigated the spatial and temporal variations of FVC Qinghai Province from 2001 2015 performed correlation analysis with annual mean temperature rainfall. results indicate that increase gradually northwest southeast are discontinuous due topographic varia...

The aim of this study was to determine the diagnostic and interpretative consequences of adopting the Global Lungs Initiative (GLI) 2012 spirometric prediction equations. We assessed spirometric records from 17 572 subjects (49.5% females), aged 18-85 years, from hospitals in Australia and Poland. We calculated predicted forced expiratory volume in 1 s (FEV1), forced expiratory volume (FVC), FE...