This study deals with characterization and quantification of form I and form II of clopidogrel bisulphate (CLP), a selective and irreversible inhibitor of ADP-induced platelet aggregation. Thermal (DSC, TGA, HSM), crystallographic (XRD) and spectroscopic (FTIR) methods were used for characterization. After characterization of active pharmaceutical ingredient (API), these techniques were further...

ATR-FTIR (Attenuated Total Reflectance Fourier Transform Infrared) spectra of prehardened epoxies with varying amounts of hardener and resin (mix ratio) have been acquired on a Midac FTIR spectrometer. The spectra form a set of training spectra for partial least-squares (PLS) analysis which was then used to analyze a series of epoxies of unknown mix ratio. The PLS model predicted the unknown mi...

Fourier transform infrared (FTIR) and circular dichroism (CD) spectroscopy are analytical techniques employed for the analysis of protein secondary structure. The use of CD spectroscopy is limited to low protein concentrations (<2 mg ml(-1)), while FTIR spectroscopy is commonly used in a higher concentration range (>5 mg ml(-1)). Here we introduce a quantum cascade laser (QCL)-based IR transmis...

Recently, spectroscopic analysis of cancer tissues has received considerable attention to be a diagnosis technique due to its sensitivity to biochemical variations in the samples. In this study Fourier Transform Infrared Spectroscopy (FTIR) was used to analyze, spectroscopicaly, a number of bladder cancer tissues compared with normal bladder tissues. Twenty samples were collected from ten patie...

Scattering-type scanning near-field optical microscopy (s-SNOM) and Fourier transform infrared nanospectroscopy (nano-FTIR) are emerging tools for nanoscale chemical material identification. Here, we push s-SNOM and nano-FTIR one important step further by enabling them to quantitatively measure local dielectric constants and infrared absorption. Our technique is based on an analytical model, wh...

In this study, we synthesized a novel multifunctional benzoxazine monomer (Coumarin-COOH BZ), possessing both coumarin and COOH groups, through the reaction of 4-methyl-7-hydroxycoumarin, 4-aminobenzoic acid, and paraformaldehyde in 1,4-dioxane, with the structure confirmed using 1H and 13C nuclear magnetic resonance and Fourier transform infrared (FTIR) spectroscopy. Differential scanning calo...

The present investigation, deals with the study of both hydrated Sulfate Resisting Portland Cement (SRPC) and fly ash (fly ash 20%, 30% and 50%) composite with two different waters. Among the three percentages of fly ash addition, 30% addition is found to be optimum. The samples (SRPC and 30% fly ash) were analyzed using the Fourier Transform Infrared Spectroscopy (FTIR) spectra. The relationsh...

A spectroscopic method for human sperm evaluation and characterization using Fourier Transform Infra Red (FTIR) is presented. The high sensitivity of FTIR to changes in chemical structure and arrangement of molecules and proteins makes it a powerful diagnostic tool. Our experimental results show that a simple MIR (400 cm−1 4000 cm−1) transmission spectrum of a human sperm is very fast and can b...