Peritoneal dialysis is limited by morphologic changes of the peritoneal membrane. Use of peritoneal dialysis fluids (PDF) that contain glucose degradation products (GDP) generates advanced glycation end-products (AGE) within the peritoneal cavity. It is unknown whether peritoneal damage is causally related to AGE-receptor for AGE (RAGE) interaction. The effects of PDF were compared with differe...

Trehalose-6-phosphate synthase OtsA from streptomycetes is unusual in that it uses GDP-glucose as the donor substrate rather than the more commonly used UDP-glucose. We now confirm that OtsA from Streptomyces venezuelae has such a preference for GDP-glucose and can utilize ADP-glucose to some extent too. A crystal structure of the enzyme shows that it shares twin Rossmann-like domains with the ...

Accurate data on gross domestic product (GDP) at pixel level are needed to understand the dynamics of regional economies. GDP spatialization is the basis of quantitative analysis on economic diversities of different administrative divisions and areas with different natural or humanistic attributes. Data from the Visible Infrared Imaging Radiometer Suite (VIIRS), carried by the Suomi National Po...

This paper uses scale-independent indicators to explore the Chinese national and regional innovation systems during economic transition. Our perception of an innovation system is frequently informed by conventional indicators based on linear assumptions while actually innovation systemsmay behave differently. Scale-independent indicators characterize non-linearpropertiesof an innovation system....

O.1 GDP, United States (millions of 1990 Geary-Khamis Dollars) O.2 GDP Volume Index, United States (2000 = 100) O.3 GDP, Argentina (millions of 1990 Geary-Khamis Dollars) O.4 GDP, Argentina (1986 pesos) O.5 GDP Volume Index, Argentina (2000 = 100) O.6 Population, United States (thousands) O.7 Population Ages 15-64, United States O.8 Population, Argentina (thousands) O.9 Population Ages 15-64, A...

Glycoproteins and lipids in the Golgi complex are modified by the addition of sugars. In the yeast Saccharomyces cerevisiae, these terminal Golgi carbohydrate modifications primarily involve mannose additions that utilize GDP-mannose as the substrate. The transport of GDP-mannose from its site of synthesis in the cytosol into the lumen of the Golgi is mediated by the VRG4 gene product, a nucleo...

We propose a role for GTP hydrolysis in microtubule assembly in which the GTPase reaction serves to stabilize tubulin subunits in the microtubule. The GTPase reaction in tubulin subunits containing GTP at microtubule ends is presumed to occur predominately in subunits at one of the interfaces between a cap of GTP-containing tubulin subunit and a core of GDP-containing tubulin subunit in the mic...

The reaction of two arginine-modifying reagents, phenylglyoxal and 2,3-butanedione, with a highly purified uncoupling protein of brown adipose tissue mitochondria decreased the GDP binding to the uncoupling protein. This inhibition was irreversible and dependent on time and concentration of the reagent. Complete inhibition of GDP binding by both reagents establishes that arginine is one of the ...

Long series of quarterly GDP ®gures are still not available for many countries. This paper suggests an empirical procedure adapted from Chow and Lin (1971) to derive quarterly estimates from annual GDP ®gures and produces quarterly GDP by sectors for Malaysia from 1973Q1 onwards. A comparison of these estimates with some univariate interpolations using published quarterly ®gures for recent year...