نتایج جستجو برای: سیتوکروم a1
تعداد نتایج: 23371 فیلتر نتایج به سال:
The RNA-binding protein hnRNP A1 is a splicing regulator produced by exclusion of alternative exon 7B from the A1 pre-mRNA. Each intron flanking exon 7B contains a high-affinity A1-binding site. The A1-binding elements promote exon skipping in vivo, activate distal 5' splice site selection in vitro and improve the responsiveness of pre-mRNAs to increases in the concentration of A1. Whereas the ...
Positron emission tomography (PET) studies have shown decreased glucose metabolism in brain regions of detoxified alcoholics and cocaine abusers. However, it is not clear whether this decrease is due to chronic drug abuse or a pre-existing condition. Molecular genetic studies have found an association of the D2 dopamine receptor (DRD2) A1 allele with alcoholism and drug abuse. Moreover, reduced...
Annexin A1 is a member of a large superfamily of glucocorticoid-regulated, calcium- and phospholipid-binding proteins. Our previous studies have shown that the abnormal expression of Annexin A1 is related to the occurrence and development of nasopharyngeal carcinoma (NPC). To understand the roles of Annexin A1 in the tumorigenesis of NPC, targeted proteomic analysis was performed on Annexin A1-...
For the iteration of spherical average (A1)N and Laplace operator Δ, we consider boundedness Δ(A1)N on α-modulation spaces \(M_{p,q}^{s,\alpha }\). The authors obtain some sufficient necessary conditions to ensure spaces. main theorems significantly improve known results.
زمینه و هدف: هپوکمپ، یکی از شایع ترین نواحی سیستم لیمبیک در ایجاد صرع لوب گیجگاهی می باشد و صرع ایجاد شده در این ناحیه می تواند از طریق قشر پیریفورم منتشر شود. آدنوزین یک ماده ضد تشنجی درونزا می باشد و اثرات ضد تشنجی خود را از طریق فعال کردن گیرنده های آدنوزینی a1 اعمال می کند. هدف از این مطالعه بررسی نقش گیرنده های آدنوزینی a1 قشر پیریفورم بر تشنج های ایجاد شده به روش کیندلینگ در ناحیه ca1 هیپ...
خرچنگ‌های جنس Charybdis ازجمله جنسهای مهم خانوادهی Portunidae میباشند که وضعیت قرارگیری آن‌ها در این خانواده همیشه موردبحث محققین مختلف بوده است. از این رو در مطالعهی حاضر ضمن بررسی توالی قطعهی یک ژن سیتوکروم اکسیداز دو گونهی C. helleri و C. lucifera به بررسی این موضوع پرداخته شد. نمونه‌برداری در سواحل خلیج چابهار در سال 1393 انجام گرفت. استخراج DNA با استفاده از روش CTAB صورت گرفت. با ا...
Monoclonal antibodies that bind to human leukocyte antigen (HLA) are useful tools for HLA-typing, tracking donor-recipient chimerisms after bone marrow transplants, and characterizing specific major histocompatibility complexes (MHC) on cell surfaces. Unfortunately, equivalent reagents are not available for rhesus macaques, which are commonly used animal as models in organ transplant and infect...
Let φ(x1, . . . , xh, y) = u1x1 + · · · + uhxh + vy be a linear form with nonzero integer coefficients u1, . . . , uh, v. Let A = (A1, . . . , Ah) be an h-tuple of finite sets of integers and let B be an infinite set of integers. Define the representation function associated to the form φ and the sets A and B as follows: R (φ) A,B (n) = card ({(a1, . . . , ah, b) ∈ A1 × · · · × Ah × B : φ(a1, ....
SP-A (surfactant protein A) is a membrane-associated SP that helps to maintain the lung in a sterile and non-inflamed state. Unlike SP-As from other mammalian species, human SP-A consists of two functional gene products: SP-A1 and SP-A2. In all the functions examined, recombinant human SP-A1 invariably exhibits lower biological activity than SP-A2. The objective of the present study was to inve...
Most individuals carry two wild-type M alleles of the SERPINA1 gene which encodes a1-antitrypsin. 95% of severe deficiency of a1-antitrypsin is associated with the Z allele (Glu342Lys; denoted PiZZ in the homozygote), and with the retention and polymerisation of a1-antitrypsin within hepatocytes [1]. These polymers are contained within periodic acid–Schiff-positive, diastase-resistant inclusion...
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