نتایج جستجو برای: سیانکس 302
تعداد نتایج: 6069 فیلتر نتایج به سال:
BACKGROUND Hypoxic niches in solid tumors harbor therapy-resistant cells. Hypoxia-activated prodrugs (HAPs) have been designed to overcome this resistance and, to date, have begun to show clinical efficacy. However, clinical HAPs activity could be improved. In this study, we sought to identify non-pharmacological methods to acutely exacerbate tumor hypoxia to increase TH-302 activity in pancrea...
Electric arc furnace dust (EAFD) of ferromanganese production units, in the form of slurry, contains tar, alkalies, manganese, zinc, iron, silica, calcium, aluminum and other elements. A hydrometallurgical route based on solvent extraction technique was investigated for selective separation of manganese from the dust. Leaching of the EAFD resulted in an aqueous feed containing 4 g/L of manganes...
Rotated and non-rotated commercial potato fields were sampled intensively to follow Colorado potato beetle, Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae), colonization and subsequent oviposition patterns in the spring of 1990 and 1991. Maximum densities of colonizing adults ranged from 0 to 14,891/ha and maximum egg mass densities ranged from 0 to 48,451/ha. Crop rotation generall...
Widespread outbreaks of the mountain pine beetle (Dendroctonus ponderosae Hopkins) in the lodgepole pine (Pinus contorta Dougl. ex Loud. var. latifolia Engelm.) forests of North America have produced stands with significant levels of recent tree mortality. The needle foliage from recently attacked trees typically turns red within one to two years of attack indicating successful colonization by ...
Bosch ist heute noch überwiegend ein Hersteller von Dingen der materiellen Welt. Was 1886 mit einfachen elektrotechnischen Apparaten begann, erstreckt sich heute über verschiedenste Anwendungsdomänen und Geschäftsbereiche. Kfz-Komponenten, Heizungsanlagen, Haushaltsgeräte und Industriesteuerungen gehören ebenso zum Produktportfolio wie Sicherheitssysteme, Beschallungsanlagen oder auch medizinte...
The efficient allocation of control rights in inter-firm collaborations is a widely emphasized issue. In this paper, I empirically identify control rights and the allocation of these rights using a unique survey data set on collaborations between biotechnology and pharmaceutical firms. Fifteen control rights are identified to make up the structure of deals with five rights being the items of co...
Each test or feature in a classification system defines a set partition on a class of objects. Adding new features refines the classification, whereas deleting features may result in merging previously distinguished classes. As an illustration, consider the set of automobile types { VW Beetle, Toyota, Lexus, Cadillac }. The feature size partitions the cars into sets of small and large cars, {{ ...
Two strains of lymphatic leukemia, J and 302, have been maintained through hundreds of successive intraperitoneal injections of spleen tissue from leukemic donors. The two strains appeared to be similar pathologically, but were chemically dissimi lar. The J leukemia had white cell counts of 500,000-1,000,000 cu. mm. with enlarged spleen and no jaundice. The 302 strain had markedly enlarged live...
MiR-302b is a member of miR-302-367 cluster. The miR-302-367 cluster played important roles in maintaining pluripotency in human embryonic stem cells (hESCs) and has been proved to be capable of suppressing cell growth in several types of cancer cell lines including Hepatocellular Carcinoma (HCC) Cell lines. However, the role that miR-302b plays in the 5-Fluorouracil (5-FU) sensitivity of HCC h...
Seth L. Blumerman 1 , and E. Fidelma Boyd 1* 10 11 Department of Biological Sciences, University of Delaware, Newark, DE 19711 1 , U.S. 12 Department of Agriculture, Agricultural Research Service, Delaware State University, Dover, 13 DE 19901 2 14 15 16 17 Corresponding author E. Fidelma Boyd – [email protected] 18 Department of Biological Sciences, 341 Wolf Hall, University of Delaware 19 Newark,...
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