نتایج جستجو برای: سوییچ ovs
تعداد نتایج: 482 فیلتر نتایج به سال:
A published model for estimating service lives of organic vapor (OV) air-purifying respirator cartridges has been extended to include multiple organic vapors at all humidities. Equilibria among the OVs are calculated using Ideal Adsorbed Solution Theory, whereas the effects of adsorbed water are considered as due to micropore volume exclusion. Solubilities of OVs in water must also be taken int...
BACKGROUND Dexmedetomidine (DEX) is a novel, highly selective α2-adrenoceptor agonist that elicits sedative, amnestic, sympatholytic and analgesic effects in patients. Several Japanese investigators have reported the clinical usefulness of DEX for sedation in endoscopic therapies for gastrointestinal malignancies; however, there have been limited data regarding the usefulness and safety of DEX ...
Introduction: Oncolytic viruses (OVs) represent a novel therapeutic strategy in oncology due to their capability selectively infect and replicate cancer cells, triggering direct and/or immune-induced tumor lysis. However, the mechanisms governing OV pharmacokinetics are still poorly understood. This work aims develop physiologically based pharmacokinetic model of OV, V937, non-tumor-bearing mic...
The use of engineered viral strains such as gene therapy vectors and oncolytic viruses (OV) to selectively destroy cancer cells is poised to make a major impact in the clinic and revolutionize cancer therapy. In particular, several studies have shown that OV therapy is safe and well tolerated in humans and can infect a broad range of cancers. Yet in clinical studies OV therapy has highly variab...
Travel time is very critical for emergency response and emergency vehicle (EV) operations. Compared to ordinary vehicles (OVs), EVs are permitted to break conventional road rules to reach the destination within shorter time. However, very few previous studies address the travel time performance of EVs. This study obtained nearly 4-year EV travel time data in Northern Virginia (NOVA) region usin...
Dendritic cells (DCs) are specialized antigen-presenting cells that have a notable role in the initiation and regulation of innate and adaptive immune responses. In the context of cancer, appropriately activated DCs can induce anti-tumor immunity by activating innate immune cells and tumor-specific lymphocytes that target cancer cells. However, the tumor microenvironment (TME) imposes different...
Oncolytic viral (OV) therapy, which uses genetically engineered tumor-targeting viruses, is being increasingly used in cancer clinical trials due to the direct cytolytic effects of this treatment that appear to provoke a robust immune response against the tumor. As OVs enter tumor cells, intrinsic host defenses have the potential to hinder viral replication and spread within the tumor mass. In ...
This study explored the comprehension and production of sentences derived by syntactic movement, in orally trained school-age Hebrew-speaking children with moderate to profound hearing impairment, aged 7;8-9;9 years. Experiments 1 and 2 tested the comprehension of relative clauses and topicalization sentences (with word orders of OVS [object, verb, subject] and OSV [object, subject, verb]) usin...
With the advancement of a growing number of oncolytic viruses (OVs) to clinical development, drug delivery is becoming an important barrier to overcome for optimal therapeutic benefits. Host immunity, tumor microenvironment and abnormal vascularity contribute to inefficient vector delivery. A number of novel approaches for enhanced OV delivery are under evaluation, including use of nanoparticle...
سیستم های میکرو الکترومکانیک ونانو الکترو مکانیک امروزه بسیار مورد توجه قرار گرفته اند.با توجه به پتانسیل بالقوه شان کاربرد های این سیستم ها رو به افزایش می باشد. سویچ های mos که امروزه در اکثر سیستم های دیجیتالی بکار می روند در واقع با اعمال الکترون به نیمه هادی یا حذف آن باعث ایجاد یک جریان یا قطع آن می شود، حال اگر نوع جدید از سوییچ که در آن قطع و وصل از طریق تونل زنی الکترون انجام شود سوییچ...
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