Low dose methotrexate (5-25 mg/week) represents a major therapeutic advance in the management of RA in the last decade. Its established efficacy has led to it being used as the lead comparator drug in slow acting anti-rheumatic drug (SAARD) trials, to its increasing use in early disease, and to its inclusion in many drug combinations currently being evaluated. It seems to be the best tolerated ...

Although educational games have revealed to be a very effective focus in diverse situations, their use in education is still very limited. In this paper we analyse the main challenges concerning educational games that, from our perspective, have to be approached so that the use of this kind of games can be widespread. These challenges are classified in three main dimensions: socio-cultural, edu...

Over the last few years the idea of using video games for serious purposes such as education, training or health has gained widespread popularity. These games are, in contrast to their commercial counterparts, often meant to be played by single players. However, it has been shown that playing in groups trains social skills, supports collaborative learning and increases motivation. Multiplayer g...

Studies of violence in stalking have treated interpersonal violence as a homogeneous phenomenon. This study was conducted to ascertain whether the associations of serious violence in stalking are the same as those of general violence in stalking. Of 85 stalkers referred to a forensic service, those who had committed acts of serious violence (homicide and serious assaults) were compared with tho...

A closer look at game-based learning reveals tensions between the two parties games and learning. Game-based learning is examined here from the perspective of one party within this relationship against the background of globalization and cultural change. Getting serious about mobile gaming this paper aims for a deeper understanding of mobile games and the particular learning potentials within t...

Tort law is a form of collective intervention into social and economic affairs that carries with it substantial costs, both public and private. These costs include higher prices for goods and services, higher taxes, and the socially undesirable consequences that tort law has on people's behavior such as the failure of companies to develop and introduce products the public wants, the wasteful an...

This report discusses some issues concerning serious games, that is, (digital) games used for purposes other than mere entertainment. The starting point is the serious games concept itself, and what the actually means. Further, serious games allow learners to experience situations that are impossible in the real world for reasons of safety, cost, time, etc., but they are also claimed to have po...