نتایج جستجو برای: ساختار hcg

تعداد نتایج: 65239  

Journal: :Human reproduction 2002
P Poikkeus V Hiilesmaa Aila Tiitinen

BACKGROUND Assisted reproduction treatment (ART) entails a risk of ectopic pregnancy and early pregnancy loss. Serum HCG has been found to be predictive of pregnancy outcome. Our aim was to assess the clinical value of a single early HCG assay in ART pregnancies taking into account the aetiology and treatment of infertility. METHODS During 1994-1999, we studied 774 embryo transfer cycles resu...

Journal: :Clinical chemistry 1991
K Spencer

In this study I investigated the analytical and clinical performance of the measurement of the free beta-subunit of choriogonadotropin (hCG) in normal pregnancies and in pregnancies affected by Down's syndrome. Free beta-hCG in maternal serum has been shown to be increased in Down's syndrome-affected pregnancies and is proportionally increased in more cases than is total hCG. This study confirm...

Journal: :Placenta 2007
K Handschuh J Guibourdenche V Tsatsaris M Guesnon I Laurendeau D Evain-Brion T Fournier

Human trophoblast differentiates into two pathways: extravillous cytotrophoblasts (EVCT) that invade the uterus wall and villous cytotrophoblasts (VCT) that fuse to form the syncytiotrophoblast (ST) involved in placental exchanges and endocrine function. It is established that hCG is produced and secreted by the ST into the maternal compartment where it plays a key endocrine role and stimulates...

Journal: :Human reproduction 2008
P A Nepomnaschy C R Weinberg A J Wilcox D D Baird

BACKGROUND Human chorionic gonadotrophin (hCG) is used to monitor pregnancy status. Yet the pattern of hCG excretion in the first week following implantation has not been adequately described. Therefore the aim of this study was to describe the average profile of hCG and its variability during the 7 days following estimated implantation in a population of naturally conceived pregnancies. METH...

Journal: :Expert opinion on medical diagnostics 2008
P Berger C Sturgeon

BACKGROUND Clinical management of pregnancy, pregnancy-related disorders and trophoblastic tumors is dependent on immunoassay measurements of the complex analyte human chorionic gonadotropin (hCG). Differences in hCG results using different methods affect clinical interpretation with potentially adverse consequences for patient care. Objectives/method: To provide an overview of factors contribu...

2005
C. Da Rocha C. Mendes de Oliveira

Deep B and R images of three Hickson Compact Groups, HCG 79, HCG 88 and HCG 95, were analyzed using a new wavelet technic to measure possible intra-group diffuse light present in these systems. The method used, OV WAV, is a wavelet technic particularly suitable to detect low-surface brightness extended structures, down to a S/N = 0.1 per pixel, which corresponds to a 5-σ-detection level in wave...

2016
Ning Xia Xin Wang Lin Liu

Human chorionic gonadotropin (hCG) has been regarded as a biomarker for the diagnosis of pregnancy and some cancers. Because the currently used methods (e.g., disposable Point of Care Testing (POCT) device) for hCG detection require the use of many less stable antibodies, simple and cost-effective methods for the sensitive and selective detection of hCG have always been desired. In this work, w...

Journal: :Clinical chemistry 1995
L Vankrieken R De Hertogh

Total human chorionic gonadotropin (hCG-hCG beta) in serum was assayed with the immulite system, a fully automated random-access immunoassay analyzer that has a unique centrifugal procedure for solid-phase washing and a chemiluminescent detection system. The broad range of the hCG calibration curve (up to 5000 IU/L) is achieved by using a small serum sample size (5 microL), which provides suffi...

Journal: :Clinical chemistry 1981
R E Wehmann S M Harman S Birken R E Canfield B C Nisula

We have devised a radioimmunoassay (RIA) for human choriogonadotropin (hCG) in first morning-voided urine specimens. Concanavalin A, a lectin, is used to extract and concentrate the hCG from urine. A high-affinity antiserum is used, directed to the hCG beta carboxy-terminal peptide, a unique immunological determinant not shared by the beta subunit of human lutropin. This ensures that urinary hu...

Journal: :The Journal of clinical endocrinology and metabolism 2009
Sarah Berndt Silvia Blacher Sophie Perrier d'Hauterive Marc Thiry Marie Tsampalas André Cruz Christel Péqueux Sophie Lorquet Carine Munaut Agnès Noël Jean-Michel Foidart

CONTEXT During the periimplantation period, human chorionic gonadotropin (hCG) plays a key role by increasing the uterine blood flow through uterine vessel vasodilatation but also through angiogenesis. Indeed, we previously demonstrated that hCG contributes to endothelial cell recruitment and vessel formation. OBJECTIVE In this study, hCG was proposed as an arteriogenic factor that could prom...

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