Hawthorn (Crataegus oxyacantha) is a widely used Chinese herb for treatment of gastrointestinal ailments and heart problems and consumed as food. In North America, the role of treatment for heart problems dates back to 1800. Currently, evidence is accumulating from various in vivo and in vitro studies that hawthorn extracts exert a wide range of cardiovascular pharmacological properties, includ...

Hyperoside, an active compound found in plants of the genera Hypericum and Crataegus, is reported to exhibit antioxidant, anticancer, and anti-inflammatory activities. Induction of hepatic stellate cell (HSC) apoptosis is recognized as a promising strategy for attenuation of hepatic fibrosis. In this study, we investigated whether hyperoside treatment can exert antifibrotic effects in human LX-...

A number of diseases affecting the heart are prevalent in canines. Acquired diseases, those which develop over the course of an animal's lifetime (rather than congenital defects present at birth), have recently been the subject of several studies to determine the efficacy of dietary supplementation on symptom presentation, disease severity, and mortality rates. Specifically, coenzyme Q10 (CoQ10...

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At a time when all knowledge is 'situated' and no longer 'universal' or 'neutral', the translation of Sheila Jasanoff's reflections about "how we should deploy for the good our profoundly human ingenuity" raises a question for Brazilian academia: how to 'situate' this reflection? If times are changing for the imperial West, it is plausible to take advantage of this time to problematize 'the pro...

Crataegus spp. are used for horticultural and medicinal purposes. The medicinal importance of Crataegus is attributed to components such as flavonoids, procyanidin, aromatic acid, and cardiotonic amines. The genetic relationships among the five Iranian Crataegus species including C. aronia, C. pontica, C. meiery, C. monogyna, and C. pentagyna were assessed using inter simple sequence repeats (IS...

6. Hawthorn (Crataegus species) 6.1. Clinical studies 6.1.1. Cardiac insufficiency 6.2. In vitro and in vivo studies 6.2.1. Inotropic effects 6.2.2. Antiarrhyythmic effects 6.2.3. Ischemic-reperfusion injury 6.2.4. Vasodilation and coronary blood flow 6.2.5. Antihypertensive effects 6.2.6. Antioxidant effects 7. Red wine (Vitis vinifera) and resveratrol