A brefeldin A (BFA)-inhibited guanine nucleotide-exchange protein (GEP) for ADP-ribosylation factors (ARF) was purified earlier from bovine brain cytosol. Cloning and expression of the cDNA confirmed that the recombinant protein (p200) is a BFA-sensitive ARF GEP. p200 contains a domain that is 50% identical in amino acid sequence to a region in yeast Sec7, termed the Sec7 domain. Sec7 domains h...

PURPOSE To evaluate with the use of corneal topographic data the differences between total corneal power calculated using ray tracing (TCP) and the Gaussian formula (GEP) in normal eyes, eyes that previously underwent laser in situ keratomileusis/photorefractive keratectomy (LASIK/PRK), and theoretical models. METHODS TCP and GEP using mean instantaneous curvature were calculated over the cen...

This writing proposes to share joyful encounters between the art of clowning and sociopsychodramatic approach. The methodology adopted was cartography accompany process experienced in Group Studies Practices Psychology, Clowning, Psychodrama (GEP). During years 2017 2018, GEP held monthly meetings for twelve months which they studied principles these two approaches inspired by performing arts. ...

Gene Expression Programming (GEP) is a new technique of Genetic Programming (GP) that implements a linear genotype representation. It uses fixed-length chromosomes to represent expression trees of different shapes and sizes, which results in unconstrained search of the genome space while still ensuring validity of the program’s output. However, GEP has some difficulty in discovering suitable fu...

Chromogranin A (CgA) is the most abundant granin in gastroenteropancreatic neuroendocrine tumors (GEP-NETs). As a tumor marker is moderately sensitive and nonspecific. Despite the limitations of testing methods, which require careful interpretation, especially in the case of gastrinomas, patients treated with somatostatin analogues, and poorly differentiated tumors, it is the best tumor marker ...

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are the second most prevalent group of advanced gastrointestinal tract tumors. Resources invested in research on this patient population have exponentially increased in recent years, and this has become one of the most attractive fields for oncological research. Several proangiogenic proteins have been found to be overexpressed in GEP-NETs...

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are relatively rare and complex neoplasms that present many clinical challenges. Most GEP-NETs are sporadic, but they can be multiple and a component of a familial syndrome. Assessment of the location and extent of GEP-NETs is crucial for management and a number of novel imaging modalities are under evaluation with the principal goal of in...