Aim of the study: The objective of this study was to evaluate the anti-inflammatory and analgesic activities of the hydro-alcoholic extract of the pods of Astragalus hamosus (HAAH), a plant used in Iranian traditional medicine, and antinociceptive effects of different fractions in animal models. Material and methods: The anti-inflammatory effect was evaluated by the rat paw edema induced by for...

Introduction: Oxytocin is a active neuropeptide of central nervous system. In this study the effects of naloxone (opioid receptor antagonist) and yohimbine (α-2 adrenergic receptor antagonist) on analgesic effect of oxytocin applied into the locus coeruleus (LC) nucleus were investigated. Methods: Adult male Wistar rats were used. Animals divided into different groups receiving saline, oxy...

Objective: Vanillosmopsis arborea Baker (Asteraceae) has high economic value from Chapada to Araripe and its bark essential oil is a potential source of alpha-bisabolol. The present study aimed to elucidate the antinociceptive and antipruritic properties of the essential oil of V. arborea Baker (EOVA) in mice. Materials and Methods: The antinociceptive activity was assessed using the capsaicin,...

Objectives: Aim of the present work was to investigate the anti-inflammatory, analgesic and antiulcer effects of red seaweed Porphyra vietnamensis (P. vietnamenis). Materials and Methods: Aqueous (POR) and alcoholic (PE) fractions were successfully isolated from P. vietnamenis. Further biological investigations were performed using a classic test of paw edema induced by carrageenan, writhing in...

Aim of the study: The objective of this study was to evaluate the anti-inflammatory and analgesic activities of the hydro-alcoholic extract of the pods of Astragalus hamosus (HAAH), a plant used in Iranian traditional medicine, and antinociceptive effects of different fractions in animal models. Material and methods: The anti-inflammatory effect was evaluated by the rat paw edema induced by for...

Since use of antinoceceptive chemical drugs for relief of pain has many side effects, medical plants seem very noticeable today. Previous findings indicate that Carum Carvi (CC) modulates pain in both animal and human. The present work investigated the effects of hydoalcoholic extract of CC on acute pain in Hot plate and Tail flick models. Albino mice (20-30 g) were used for this study. Hydroal...