BACKGROUND The present study compares the protective properties of aqueous extracts of six medicinal plants, Phyllanthus emblica, Terminalia chebula (black and yellow), Terminalia arjuna, Balsamodendron Mukul and Alium sativum against lipid per-oxidation in mice brain. METHODS The antioxidant activities were analyzed by lipid per-oxidation assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical a...

Background: Hyperandrogenism and insulin resistance are the main manifestations of polycystic ovary syndrome (PCOS), which appears to be caused by exposure to androgenized models have developed and investigated to study the etiology of polycystic ovary syndrome. Objective: To evaluate the modulatory effects of Commiphora wightii (C.wightii) resins in response to hyperandrogenism in polycystic o...

The biblical balm of Gilead (Commiphora gileadensis) was investigated in this study for anticancerous activity against tumor cell lines. The results obtained from ethanol-based extracts and from essential oils indicated that β-caryophyllene (trans-(1R,9S)-8-methylene-4,11,11-trimethylbicyclo[7.2.0]undec-4-ene) is a key component in essential oils extracted from the balm of Gilead. β-Caryophylle...

Oleo-gum resins such as frankincense and myrrh are some of the economically and culturally valuable products obtained from trees and shrubs of the genera Boswellia and Commiphora, respectively. They are important natural plant products used in several industries that include pharmacology, food, flavour, liqueur and beverage, cosmetics, perfumery and others. Moreover, frankincense and myrrh have...

Commiphora species are of high medicinal importance. They distributed in Saudi Arabia, mainly rocky habitats and regions under mountains, including the east Tihama, forming a distinct element flora. The present study focuses on botanical characterization five Commiphora, i.e., C. erythraea, gileadensis, kataf, myrrha, quadricincta. morphological characters for each were recorded comparatively, ...

Arthritis, an inflammation of the joints, is usually a chronic disease that results from dysregulation of pro-inflammatory cytokines (e.g. tumour necrosis factor and interleukin-1beta) and pro-inflammatory enzymes that mediate the production of prostaglandins (e.g. cyclooxygenase-2) and leukotrienes (e.g. lipooxygenase), together with the expression of adhesion molecules and matrix metalloprote...

The title triterpene compound, C(23)H(32)O(4), isolated from Commiphora wightii features four trans-fused rings, among which the five-membered ring adopts an envelope conformation, the cyclo-hexene ring adopts a half-chair conformation and the two cyclo-hexane rings exist in chair conformations. The asymmetric unit contains two independent mol-ecules. Weak inter-molecular C-H⋯O hydrogen bonding...

The volatile components of the leaves of five Bursera species, B. copallifera, B. exselsa, B. mirandae, B. ruticola and B. fagaroides var. purpusii were determined by gas chromatography-mass spectrometry (GC-MS). Germacrene D was one of the predominant components (15.1-56.2%) of all of these species. Germacrene D has also been found in other Bursera species and some species of Commiphora, the s...

Fractionation of a steam distilled residue of Commiphora confusa resin has yielded four novel dammarane triterpenes characterised as (20S)-3beta-acetoxy-12beta,16beta-trihydroxydammar-24-ene, (20S)-12beta,16beta-trihydroxydammar-24-ene-3beta-O-beta-glucopyranoside, (20S)-3beta-acetoxy-12beta,16beta,25-tetrahydroxydammar-23-ene, and (20S)-3beta,12beta,16beta,25-pentahydroxydammar-23-ene. The kno...