نتایج جستجو برای: راکتیو نارنجی 122
تعداد نتایج: 16944 فیلتر نتایج به سال:
Previous studies indicate that microRNA-122 (miR-122) is down-regulated in several cancer cells and regulates cell apoptosis, proliferation, metastasis, and tumor angiogenesis. However, the mount of miR-122 in bladder cancer and the pivotal molecular mechanisms of miR-122 used to regulate bladder carcinogenesis and angiogenesis remain to be clarified. Here, we reveal that miR-122 expression is ...
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate a variety of biological processes. Recently, human liver-specific miRNA miR-122 has been reported to facilitate hepatitis C virus (HCV) replication in liver cells. HCV is one of the leading causes of liver diseases worldwide. In Pakistan, the estimated prevalence is up to 10%. Here, we report hepatic and serum miR-122 expression profil...
The regulation mechanism and significance of microRNA-122 (miRNA-122) expression are unclear. The aim of this study was to investigate the effects of DNA methylation on liver-specific miRNA-122 expression, cell proliferation, and apoptosis in hepatocellular carcinoma. Methylation of the miRNA-122 promoter region was detected through methylation sequencing. The level of miRNA-122 expression was ...
Type I interferon (IFN) is believed to play significant roles in limiting tumor growth. It has been revealed that the induction of endogenous IFN expression is one of the key mechanisms for successful IFN therapy. However, recent studies have shown that the efficacy of type I IFN therapy has limitations in the clinical treatment of certain tumors, including hepatocellular carcinoma (HCC). It ha...
The liver-specific microRNA miR-122, which has essential roles in liver development and metabolism, is a key proviral factor for hepatitis C virus (HCV). Despite its crucial role in the liver and HCV life cycle, little is known about the molecular mechanism of miR-122 expression regulation by HCV infection. Here, we show that the HCV core protein downregulates the abundance of miR-122 by promot...
miRNAs are emerging as critical regulators in carcinogenesis and tumor progression. Recently, microRNA-122 (miR-122) has been proved to play an important role in hepatocellular carcinoma, but its functions in the context of breast cancer (BC) remain unknown. In this study, we report that miR-122 is commonly downregulated in BC specimens and BC cell lines with important functional consequences. ...
Hepatitis C virus subverts liver-specific microRNA, miR-122, to upregulate viral RNA abundance in both infected cultured cells and in the liver of infected chimpanzees. These findings have identified miR-122 as an attractive antiviral target. Thus, it is imperative to know whether a distinct functional complex exists between miR-122 and the viral RNA versus its normal cellular target mRNAs. Tow...
در این مقاله، مسئله پیشنهاددهی نیروگاه مجازی در بازار انرژی و خدمات جانبیِ رزرو چرخان و توان راکتیو به صورت همزمان بررسی شدهاست. بدین منظور مدلی غیرتعادلی بر اساس درمدار قرار دادن قیمت بنیان واحدها مقید به قیود امنیت (scpbuc)[i] که تعادل عرضه- تقاضا و امنیت داخلی نیروگاه مجازی را به حساب می آورد، ارائه شده است. با استفاده از مدل ارائه شده نیروگاه مجازی از یک سو برای بهرهبردار سیستم توزیع، خ...
پژوهش حاضر، به منظور بررسی اثرات جیبرلیک اسید (ga3) و متیل جاسمونات (mj) از تنظیم کننده های رشد گیاهی بر بیوسنتز رنگیزه های دو رقم گل همیشه بهار (‘little ball orange’, ‘little ball yellow’) در دانشگاه گیلان در سال 1389 انجام شد. نتایج حاصل نشان داد که ارتفاع گیاه، وزن تر گل ها، تعداد گل، قطر گل، و قطر ساقه گل، درصد ماده خشک، ظرفیت آنتی اکسیدانی، میزان کاروتنوئید کل، میزان فلاونوئید (کاتچین و کو...
Human Papillomavirus (HPV) 16 infection is considered as one of the significant causes of human cervical cancer. The expression of the viral oncogenes like E6 and E7 play an important role in the development of the cancer. MiR-122 has been reported to exhibit a strong relationship with hepatitis viruses and take part in several tumor development, while the effects of miR-122 on HPV infection an...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید